Periplaneta americana Extracts Promote Skin Wound Healing via Nuclear Factor Kappa B Canonical Pathway and Extracellular Signal-Regulated Kinase Signaling

Figure 6

PAE affected wound healing in cutaneous thermal burns in vivo. In the C57 mouse model of thermal injury, the left wound of the dorsal flank was treated with PAE (5 mg/mL) while the right side treated with normal saline served as the daily control. (a) Representative images of thermal injury on days 0, 7, 14, and 21; (b) histological HE staining of differentially treated tissues on days 0, 7, 14, and 21; (c) healing rate of thermal wound. < 0.05 versus control group.

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