Oral Administration of Tualang and Manuka Honeys Modulates Breast Cancer Progression in Sprague-Dawley Rats Model
Table 7
The haematological parameters of TH and MH treated groups compared with negative and positive controls.
Groups
value
1 −ive control
2 +ive control
3 (1.0 g/kg TH)
4 (1.0 g/kg MH)
RBC (1012/L)
7.35 (0.42)
5.1 (0.9)
6.8 (3.32)
6.15 (2.75)
0.003
Hb (g/dl)
15.2 (0.77)
11.35 (1.42)
13.85 (5.95)
13.85 (4.45)
0.003
PCV (%)
46 (3.25)
35 (8.25)
42.5 (17.75)
43.5 (12.25)
0.009
MCV (fl)
68.5 (3.25)
65 (4.75)
65 (11.75)
67 (10.25)
0.013
MCH (pg)
20.5 (1)
21 (2)
21 (3)
21 (3.5)
0.169
MCHC (g/L)
32 (1)
31.5 (2.25)
32 (3.5)
31.5 (2.25)
0.062
RDW (%)
11.9 (1.57)
13.95 (1.72)
12.25 (2.17)
12.65 (2.1)
0.01
TWBC (109/L)
4.75 (1.75)
6.4 (7.52)
4.82 (8.75)
7.35 (6.85)
0.02
Polymorphs (%)
32 (8.75)
46.5 (18)
31.5 (11.25)
31.5 (9.5)
0.01
Lymphocytes (%)
68 (8)
49 (19.25)
69 (9.75)
67.5 (4.5)
0.014
Monocytes (%)
2 (1.5)
2.5 (3.5)
0.5 (1)
1 (4.25)
0.231
Eosinophils (%)
0 (1)
0 (1.25)
0.5 (1)
1 (0.25)
0.102
Basophils (%)
0
0
0
0
1
Platelets’ (109/L)
839 (225.75)
627.5 (196.75)
666.5 (229.25)
540.5 (324.75)
0.01
Kruskal-Wallis test. Data are expressed as median interquartile range (IqR). Values are statistically significant when . FBC: full blood count, RBC: red blood cells, Hb: haemoglobin, PCV: packed cell volume, MCV: mean corpuscular volume, MCH: mean corpuscular haemoglobin, MCHC: mean corpuscular haemoglobin concentration, RDW: red cell distribution width, TH: Tualang honey, MH: Manuka honey, −ive control: normal rats, and +ive control: group bearing breast cancer but received no honey treatment.
