Fuzheng Quxie Decoction Ameliorates Learning and Memory Impairment in SAMP8 Mice by Decreasing Tau Hyperphosphorylation

Table 2

FQD components detected via LC-MS/MS (ng/mL).

Component	Plasma level	Brain level
Ginseng
Ginsenoside Rg1	2.63	1.58
Ginsenoside Re	2.63	4.47
Ginsenoside Rb1	10.7~282	ND
Huanglian
Coptisine	0.793~94.2	0.767~3.3
Berberine	9.54~13.9	<LLOQ
Chuanxiong
Ferulic acid	0.36~22.5	ND

Note. ND, not detected; <LLOQ, lower limit of quantitation. Ginsenoside Rg1 and ginsenoside Re were detected in one plasma sample and one brain tissue homogenate sample.