Review Article

A Systematic Review of Intervention Studies Examining Nutritional and Herbal Therapies for Mild Cognitive Impairment and Dementia Using Neuroimaging Methods: Study Characteristics and Intervention Efficacy

Table 4

Risk of bias ratings for included studies. Studies are detailed in alphabetical order of authors’ names. Studies with low risk of bias (total scores ≥ 9) are italicised.

StudyItem 1Item 2Item 3Item 4Item 5Item 6Item 7Item 8Item 9Item 10Total

Bi et al. (2011)00101111005
Cohen et al. (2003)00101111005
de Waal et al. (2014)111111111110
Douaud et al. (2013)11111111109
Heo et al. (2016)00100001103
Hofferberth (1994)00000001001
Jernerén et al. (2015)11111111109
Köbe et al. (2015)00100111105
Matsuoka et al. (2012)00101111106
Muresanu et al. (2010)00100011003
Nilsson et al. (2000)00101101004
Oishi et al. (1998)00000001102
Onofrj et al. (2002)00111001105
Saletu et al. (1995)00101011116
Smith et al. (2010)111111111110
Thomas et al. (2001)10001111005
Tsolaki et al. (in press)00000000001
Yamaguchi et al. (2004)00000001001
Zhang et al. (2015)00110111106
Zhang et al. (2014)00110111106
Zhang et al. (2012)10101001004

Note. Items rated as yes scored 1, and items rated as no or unable to determine both scored 0. Lower scores indicate a higher risk of bias.