Research Article
Transient Expression of Lumbrokinase (PI239) in Tobacco (Nicotiana tabacum) Using a Geminivirus-Based Single Replicon System Dissolves Fibrin and Blood Clots
Figure 5
In vitro human blood-clot lysis assay. (a) Recombinant PI239 dissolved human blood clot. (b) Percentage of blood-clot lysis. PBS: 1x Phosphate Buffered Saline; −CK: elution from noninfiltrated leaf (negative control); WT: pBYR-WT-PI239; OP: pBYR-LPH-OP-PI239. LK: standard lumbrokinase (18,000 u/mg). Values represent the means ± SE. Different letters indicate significant differences (; ; one-way ANOVA test).
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