Research Article

Serum and Liver Tissue Metabonomic Study on Fatty Liver in Rats Induced by High-Fat Diet and Intervention Effects of Traditional Chinese Medicine Qushi Huayu Decoction

Table 2

Summary of potential biomarkers.

MetabolitesModel groupaQSHY groupb

SerumTetradecanoic acid
Oleic acid
Glycerol
Glycine↑##
Homoserine↑##
Pyruvic acid↑#
Docosahexaenoic acid
Ribose
Adenine↑#
beta-Alanine↑##
N-Acetylglutamic acid↑##
Myo-inositol
3-Phosphoglyceric acid
Fumaric acid
Malic acid↑#
Adenosine↑#
Glutaric acid↑#
Glyceric acid
Glycerol-2-phosphate↑#
Aspartic acid↑#

Liver tissueTetradecanoic acid
Oleic acid
Glycerol
Glycine↑##
Cholesterol↓##
N-Acetylglutamic acid↑##
Campesterol↑##
Glutaric acid↑##
4-Aminobutyric acid↑##
Adenosine↑#
Adenine↑#
Pyruvic acid↑#
Glycerol-2-phosphate↑#
Ribose↑#
Docosahexaenoic acid
Myo-inositol
3-Phosphoglyceric acid
Malic acid
Fumaric acid

The up or down arrows represent the relatively increased or decreased levels of the metabolites in model group or QSHY group, respectively. to the control group. to the model group. , , , and .