Serum and Liver Tissue Metabonomic Study on Fatty Liver in Rats Induced by High-Fat Diet and Intervention Effects of Traditional Chinese Medicine Qushi Huayu Decoction
Table 2
Summary of potential biomarkers.
Metabolites
Model groupa
QSHY groupb
Serum
Tetradecanoic acid
↑
↓
Oleic acid
↑
↓
Glycerol
↑
↓
Glycine
↓
↑##
Homoserine
↓
↑##
Pyruvic acid
↓
↑#
Docosahexaenoic acid
↓
↑
Ribose
↓
↑
Adenine
↓
↑#
beta-Alanine
↓
↑##
N-Acetylglutamic acid
↓
↑##
Myo-inositol
↓
↑
3-Phosphoglyceric acid
↓
↑
Fumaric acid
↓
↑
Malic acid
↓
↑#
Adenosine
↓
↑#
Glutaric acid
↓
↑#
Glyceric acid
↓
↑
Glycerol-2-phosphate
↓
↑#
Aspartic acid
↓
↑#
Liver tissue
Tetradecanoic acid
↑
↓
Oleic acid
↑
↓
Glycerol
↑
↓
Glycine
↓
↑##
Cholesterol
↑
↓##
N-Acetylglutamic acid
↓
↑##
Campesterol
↓
↑##
Glutaric acid
↓
↑##
4-Aminobutyric acid
↓
↑##
Adenosine
↓
↑#
Adenine
↓
↑#
Pyruvic acid
↓
↑#
Glycerol-2-phosphate
↓
↑#
Ribose
↓
↑#
Docosahexaenoic acid
↓
↑
Myo-inositol
↓
↑
3-Phosphoglyceric acid
↓
↑
Malic acid
↓
↑
Fumaric acid
↓
↑
The up or down arrows represent the relatively increased or decreased levels of the metabolites in model group or QSHY group, respectively. to the control group. to the model group. , , , and .