Dahuang Zhechong Pill Combined with Doxorubicin Induces Cell Death through Regulating Energy Metabolism in Human Hepatocellular Carcinoma Cells

Figure 2

Impacts of DHZCP-medicated serum and/or DOX on SMMC-7721 cell apoptosis and necrosis. (a) and (c) Flow cytometric analyses. (b) and (d) Apoptotic and necrotic indices of SMMC-7721 dealt with DHZCP with or without DOX. Groups: (1) control; (2) DHZCP-medicated serum; (3)–(5) DOX (0.5, 2, and 8 μM); (6)–(8) combination of DHZCP-medicated serum with DOX (0.5, 2, and 8 μM). Significance: , versus control; compared with DOX group.

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