Quantitative Analysis and Biological Efficacies regarding the Neuroprotective and Antineuroinflammatory Actions of the Herbal Formula Jodeungsan in HT22 Hippocampal Cells and BV-2 Microglia
Table 4
Cytotoxicity of JDS and its herbal components against HT22 and BV-2 cells (% of control).
Cells
μg/mL
12.5
25
50
100
Mean
SEM
Mean
SEM
Mean
SEM
Mean
SEM
HT22
JDS
102.20
1.77
103.15
3.38
100.16
4.42
91.96
5.34
US
95.87
1.85
92.96
1.36
95.87
2.52
85.72
2.34
CM
104.71
1.62
95.27
0.84
88.40
1.69
82.05
0.81
ZO
97.89
1.82
91.13
0.94
92.21
4.85
77.90
3.35
PG
103.40
1.20
105.66
1.90
103.74
2.34
100.03
2.30
PT
105.27
1.92
110.40
1.29
114.69
1.57
125.25
1.60
CU
96.42
1.29
97.49
0.96
100.73
1.53
109.72
2.90
PC
93.86
0.80
94.23
1.84
91.99
1.68
84.93
1.44
BV-2
JDS
97.98
2.52
99.30
2.21
95.31
5.27
94.53
3.29
US
108.86
4.90
107.62
3.14
109.28
7.00
88.21
3.84
CM
94.64
6.92
89.48
2.78
77.09
4.26
75.22
2.66
ZO
97.21
3.72
94.25
3.63
88.73
8.35
60.73
1.63
PG
120.32
7.98
108.30
4.20
106.74
5.41
93.96
3.13
PT
128.87
2.90
123.15
3.95
142.12
6.39
143.02
4.74
CU
112.59
5.99
108.59
10.16
109.73
3.94
107.30
2.15
PC
132.52
10.35
111.75
6.64
111.81
13.52
100.52
10.66
The results are expressed as mean ± SEM of three independent experiments; SEM, standard error of the mean.
