Evidence-Based Complementary and Alternative Medicine / 2017 / Article / Tab 3

Research Article

Antinociceptive Activities of the Methanolic Extract of the Stem Bark of Boswellia dalzielii Hutch. (Burseraceae) in Rats Are NO/cGMP/ATP-Sensitive-K+ Channel Activation Dependent

Table 3

Effect of BDME on serum parameters in vincristine induced neuropathic pain in rats.

Dose
(mg/kg)
ALP
(U/l)
ALT
(U/l)
AST
(U/l)
Creatinine
(mg/dl)

Normal control-72.80 ± 1.8341.20 ± 2.5644.00 ± 2.030.41 ± 0.03
Vincristine + vehicle-481.00 ± 9.68182.00 ± 7.23136.00 ± 3.030.87 ± 0.01
Vincristine + Morphine5186.00 ± 27.7085.00 ± 4.1897.00 ± 3.030.58 ± 0.03
Vincristine + BDME50087.00 ± 2.6848.40 ± 2.1674.40 ± 2.230.41 ± 0.03

ALP: alkaline phosphatase; AST: aminotransferase; ALT: alanine aminotransferase. Each value represents the mean ± ESM for six animals and analyzed by two-way ANOVA followed by Tukey post hoc test, when compared to normal control, when compared to vincristine and vehicle.