Antidepressant-Like Effect of Selected Egyptian Cultivars of Flaxseed Oil on a Rodent Model of Postpartum Depression
Table 5
Effect of different treatments on the hippocampal redox state.
Groups
Enzymatic defense system
Nonenzymatic defense system
Markers of oxidative stress
SOD
CAT
GSH
Vit. C
PC
MDA
NO
Sham
4.23 ± 0.09
71.2 ± 1.36
1.20 ± 0.02
1.54 ± 0.08
1.36 ± 0.05
13.7 ± 0.45
4.11 ± 0.16
PPD
3.09 ± 0.11
54.1 ± 1.74
0.98 ± 0.05
1.21 ± 0.02
1.78 ± 0.10
17.1 ± 0.47
7.44 ± 0.15
PPD + F5
3.90 ± 0.08
65.7 ± 1.55
1.14 ± 0.03
1.43 ± 0.05
1.47 ± 0.06
14.7 ± 0.47
4.59 ± 0.25
PPD +F6
3.81 ± 0.11
64.2 ± 1.88
1.12 ± 0.03
1.39 ± 0.04
1.49 ± 0.06
15.2 ± 0.25
4.83 ± 0.16
PPD + FLX
3.63 ± 0.25
65.8 ± 1.75
1.17 ± 0.03
1.43 ± 0.02
1.52 ± 0.07
14.2 ± 0.29
4.70 ± 0.19
Each value represents the mean of 8 rats ± SE. In the same column, the different letters indicate a significant difference between groups using one-way ANOVA by using SPSS software (version 22) followed by Duncan’s multiple-comparison test at . PPD: postpartum depression; G9 and G10: flaxseed oils from cultivars Giza 9 and Giza 10; and FLX: fluoxetine.