Electroacupuncture Alleviates Postoperative Cognitive Dysfunction in Aged Rats by Inhibiting Hippocampal Neuroinflammation Activated via Microglia/TLRs Pathway

<div>Effects of EA treatment on the levels of TLR4 in the hippocampus. (a) Changes in the expression of TLR4 protein levels in the hippocampus at different time points in the control, surgery control, surgery + drug, and surgery + EA groups. (b) The bars represent the mean ± SD. Three rats were included in each group. 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(c) Double-immunofluorescence staining of CD11b (red) together with TLR4 (green) in the hippocampal CA1, CA3, and DG region on postoperatively day 3 in the surgery control group. Scale bar for vertical panels 3 and 4 = 100 <i>μ</i>m and 10 <i>μ</i>m, respectively.</div>

Evidence-Based Complementary and Alternative Medicine

fig3

Figure 3

Figure 3: Electroacupuncture Alleviates Postoperative Cognitive Dysfunction in Aged Rats by Inhibiting Hippocampal Neuroinflammation Activated via Microglia/TLRs Pathway 

Figure 3 | Electroacupuncture Alleviates Postoperative Cognitive Dysfunction in Aged Rats by Inhibiting Hippocampal Neuroinflammation Activated via Microglia/TLRs Pathway 