Compounds from Cynomorium songaricum with Estrogenic and Androgenic Activities Suppress the Oestrogen/Androgen-Induced BPH Process

Figure 4

CS extract inhibited the estrogen-androgen induced-BPH progress in vivo. (a) The prostatic morphologies and (b) the prostatic index of rats were shown and calculated in sham-operated group, BPH model, and CS groups. (c) The pathophysiology of rat prostate was analyzed by HE staining in sham-operated group, BPH model, and CS groups. (d) The mRNA and (e) protein expressions and (f) distributions of PCNA in prostate tissues were investigated and quantified by RT-qPCR, western blot, and immunohistochemical staining. Compare with sham-operated group, , ; Compare with BPH model, .

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