Methods of Biotyping of Streptococcus mutans Species with the Routine Test as a Prognostic Value in Early Childhood Caries

Table 10

The average values of MIC, MIC range, and MIC₅₀ (mg/L) for selected antibiotics according to S. mutans clusters/biotypes set out in the clusterization method.

	Clusters from the clusterization method
	A	B	C
All strains
Amoxicillin
MIC, range	0.015–0.05	0.007–0.5	0.007–0.5
MIC50	0.05	0.05	0.05
MIC, mean	0.012	0.085	0.09
Cefazolin
MIC, range	0.03–0.1	0.02–1.5	0.02–1.5
MIC50	0.07	0.07	0.07
MIC, mean	0.15	0.153	0.16
Teicoplanin
MIC, range	0.1–1	0.1–.5	0.1–1.5
MIC50	0.5	0.5	0.5
MIC, mean	0.7	0.729	0.69
Erythromycin
MIC, range	0.04–0.07	0.015–1	0.015–1
MIC50	0.07	0.07	0.07
MIC, mean	0.05	0.092	0.151
Noncavitated group
Amoxicillin
MIC, range	N/A	0.007–0.5	0.007–0.5
MIC50		0.05	0.05
MIC, mean		0.089	0.083
Cefazolin
MIC, range		0.02–1.5	0.02–1.5
MIC50		0.07	0.07
MIC, mean		0.152	0.154
Teicoplanin
MIC, range		0.1–1.5	0.1–1.5
MIC50		0.5	0.5
MIC, mean		0.737	0.724
Erythromycin
MIC, range		0.015–1	0.015–1
MIC50		0.07	0.07
MIC, mean		0.082	0.1
Cavitated group
Amoxicillin
MIC, range	0.015–0.05	0.007–0.5	0.007–0.5
MIC50	0.05	0.05	0.04
MIC, mean	0.012	0.074	0.107
Cefazolin
MIC, range	0.03–0.1	0.02–1.5	0.02–1.5
MIC50	0.07	0.07	0.08
MIC, mean	0.15	0.156	0.175
Teicoplanin
MIC, range	0.1–1	0.1–1.5	0.1–1.5
MIC50	0.5	0.5	0.35
MIC, mean	0.7	0.699	0.611
Erythromycin
MIC, range	0.04–0.07	0.015–1	0.015–1
MIC50	0.07	0.07	0.07
MIC, mean	0.05	0.126	0.271