Standardized<i> Kaempferia parviflora</i> Extract Inhibits Intrinsic Aging Process in Human Dermal Fibroblasts and Hairless Mice by Inhibiting Cellular Senescence and Mitochondrial Dysfunction

<div>Effect of KPE on the PI3K/AKT pathway. Hs68 cells were pretreated with KPE (1–10 <i>μ</i>g/ml) or resveratrol (10 <i>μ</i>M) for 24 h. After 2 h of H<sub>2</sub>O<sub>2</sub> exposure, the cells were cultured for an additional 24 h. Protein expression of associated markers in the PI3K/AKT signaling pathway was evaluated via western blotting. The effect of KPE on (a) PI3K and AKT activation and (b) the levels of mTOR and FoxO3a are shown. <i>α</i>-Tubulin was used as the loading control.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 3: Standardized<i> Kaempferia parviflora</i> Extract Inhibits Intrinsic Aging Process in Human Dermal Fibroblasts and Hairless Mice by Inhibiting Cellular Senescence and Mitochondrial Dysfunction 

Figure 3 | Standardized Kaempferia parviflora Extract Inhibits Intrinsic Aging Process in Human Dermal Fibroblasts and Hairless Mice by Inhibiting Cellular Senescence and Mitochondrial Dysfunction 