Standardized Kaempferia parviflora Extract Inhibits Intrinsic Aging Process in Human Dermal Fibroblasts and Hairless Mice by Inhibiting Cellular Senescence and Mitochondrial Dysfunction

<div>Effect of KPE on inflammatory mediators. Hs68 cells were pretreated with KPE (1–10 μg/ml) or resveratrol (10 μM) for 24 h. After 2 h of H2O2 exposure, the cells were cultured for additional 24 h. (a) Transcriptional changes in IL-6 and IL-8 were detected via RT-PCR. (b) Protein levels of NF-κB and COX-2 were evaluated via western blotting. GAPDH and α-tubulin were used as the mRNA and protein loading controls, respectively.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 5

Figure 5: Standardized Kaempferia parviflora Extract Inhibits Intrinsic Aging Process in Human Dermal Fibroblasts and Hairless Mice by Inhibiting Cellular Senescence and Mitochondrial Dysfunction

Figure 5 | Standardized Kaempferia parviflora Extract Inhibits Intrinsic Aging Process in Human Dermal Fibroblasts and Hairless Mice by Inhibiting Cellular Senescence and Mitochondrial Dysfunction 