Standardized Kaempferia parviflora Extract Inhibits Intrinsic Aging Process in Human Dermal Fibroblasts and Hairless Mice by Inhibiting Cellular Senescence and Mitochondrial Dysfunction

Figure 6

Effects of KPE on ATP and ROS production in vitro. Hs68 cells were pretreated with KPE (1–10 μg/ml) or resveratrol (10 μM) for 24 h. After 2 h of H₂O₂ exposure, the cells were cultured for an additional 24 h. (a) Effect of KPE on ATP production. (b) Effect of KPE on ROS production. Data are represented as mean ± SD of triplicate independent experiments. ^##p < 0.01 compared to the nontreated control; < 0.05 and < 0.01 compared to the H₂O₂-treated control.

(a)

(b)