Yin-Cold or Yang-Heat Syndrome Type of Traditional Chinese Medicine Was Associated with the Epidermal Growth Factor Receptor Gene Status in Non-Small Cell Lung Cancer Patients: Confirmation of a TCM Concept
Table 3
Clinical characteristics of 292 patients classified by the cluster analysis.
Group A
Group B
p
Symptoms and signs
Intolerance of cold
81 (61.4%)
52 (32.5%)
<0.001
Fresh taste
80 (60.6%)
60 (37.5%)
<0.001
Weakness
78 (59.1%)
65 (40.6%)
Teeth-prints at the tongue edge
76 (57.6%)
53 (33.1%)
<0.001
Expectoration
76 (57.6%)
113 (70.6%)
Yellow tongue coating
52 (39.4%)
110 (68.8%)
<0.001
Thick tongue coating
54 (40.9%)
102 (63.8%)
<0.001
Dry lips
63 (47.7%)
102 (63.8%)
Slippery pulse
25 (18.9%)
97 (60.6%)
<0.001
Deep-colored urine
74 (56.1%)
90 (56.3%)
Red tongue
31 (23.5%)
86 (53.8%)
<0.001
TCM syndrome type
Yin-cold
98 (74.24%)
66 (41.25%)
<0.001
Yang-heat
34 (25.76%)
94 (58.75%)
EGFR gene status
Wild type
69 (54.33%)
110 (71.43%)
0.003
Mutated type
58 (45.67%)
44 (28.57%)
Spearman correlation coefficient: 0.331, . Group A = 0 and group B = 1; Yin-cold = 0, Yang-heat = 1. Spearman correlation coefficient: , . Group A = 0 and group B = 1; wild = 0, mutated = 1.
