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Evidence-Based Complementary and Alternative Medicine
Volume 2017, Article ID 7185649, 39 pages
https://doi.org/10.1155/2017/7185649
Review Article

Southeast Asian Medicinal Plants as a Potential Source of Antituberculosis Agent

Centre of Research for Sustainable Uses of Natural Resources (CoR-SUNR), Faculty of Science, Technology and Human Development, Universiti Tun Hussein Onn Malaysia (UTHM), 86400 Parit Raja, Batu Pahat, Johor, Malaysia

Correspondence should be addressed to Mohd Fadzelly Abu Bakar; ym.ude.mhtu@yllezdaf

Received 24 January 2017; Revised 23 April 2017; Accepted 18 May 2017; Published 3 July 2017

Academic Editor: Ghee T. Tan

Copyright © 2017 Shuaibu Babaji Sanusi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Despite all of the control strategies, tuberculosis (TB) is still a major cause of death globally and one-third of the world’s population is infected with TB. The drugs used for TB treatment have drawbacks of causing adverse side effects and emergence of resistance strains. Plant-derived medicines have since been used in traditional medical system for the treatment of numerous ailments worldwide. There were nine major review publications on antimycobacteria from plants in the last 17 years. However, none is focused on Southeast Asian medicinal plants. Hence, this review is aimed at highlighting the medicinal plants of Southeast Asian origin evaluated for anti-TB. This review is based on literatures published in various electronic database. A total of 132 plants species representing 45 families and 107 genera were reviewed; 27 species representing 20.5% exhibited most significant in vitro anti-TB activity (crude extracts and/or bioactive compounds 0–<10 µg/ml). The findings may motivate various scientists to undertake the project that may result in the development of crude extract that will be consumed as complementary or alternative TB drug or as potential bioactive compounds for the development of novel anti-TB drug.