Table of Contents Author Guidelines Submit a Manuscript
Evidence-Based Complementary and Alternative Medicine
Volume 2017 (2017), Article ID 7272947, 8 pages
https://doi.org/10.1155/2017/7272947
Research Article

Methanol Extract of Holarrhena antidysenterica Inhibits the Growth of Human Oral Squamous Cell Carcinoma Cells and Osteoclastogenesis of Bone Marrow Macrophages

1Department of Applied Life Science, The Graduate School, Yonsei University, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 120-749, Republic of Korea
2Department of Oral Biology, Oral Cancer Research Institute, BK21 PLUS Project, Yonsei University College of Dentistry, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 120-749, Republic of Korea
3Department of Oral Pathology, Yonsei University College of Dentistry, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 120-749, Republic of Korea
4Postgraduate Institute of Science, University of Peradeniya, 20400 Peradeniya, Sri Lanka
5Department of Chemistry, Faculty of Science, University of Peradeniya, 20400 Peradeniya, Sri Lanka
6Department of Oral Pathology, Faculty of Dental Sciences, University of Peradeniya, 20400 Peradeniya, Sri Lanka

Correspondence should be addressed to Won-Yoon Chung

Received 30 May 2017; Revised 19 October 2017; Accepted 31 October 2017; Published 22 November 2017

Academic Editor: Luigi Milella

Copyright © 2017 Heein Yoon et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. R. Lambert, C. Sauvaget, M. De Camargo Cancela, and R. Sankaranarayanan, “Epidemiology of cancer from the oral cavity and oropharynx,” European Journal of Gastroenterology & Hepatology, vol. 23, no. 8, pp. 633–641, 2011. View at Publisher · View at Google Scholar · View at Scopus
  2. K. R. Coelho, “Challenges of the oral cancer burden in India,” Journal of Cancer Epidemiology, vol. 2012, Article ID 701932, 17 pages, 2012. View at Publisher · View at Google Scholar · View at Scopus
  3. Y. Tada, S. Kokabu, G. Sugiyama et al., “The novel IκB kinase β inhibitor IMD-0560 prevents bone invasion by oral squamous cell carcinoma,” Oncotarget , vol. 5, no. 23, pp. 12317–12330, 2014. View at Publisher · View at Google Scholar · View at Scopus
  4. P. A. Reichart and T. H. Way, “Oral cancer and pre-cancer in Myanmar: A short review,” Journal of Oral Pathology & Medicine, vol. 35, no. 4, pp. 193–196, 2006. View at Publisher · View at Google Scholar · View at Scopus
  5. S. V. K. Rao, G. Mejia, K. Roberts-Thomson, and R. Logan, “Epidemiology of oral cancer in Asia in the past decade - An update (2000-2012),” Asian Pacific Journal of Cancer Prevention, vol. 14, no. 10, pp. 5567–5577, 2013. View at Publisher · View at Google Scholar · View at Scopus
  6. M. Ishikuro, K. Sakamoto, K. Kayamori et al., “Significance of the fibrous stroma in bone invasion by human gingival squamous cell carcinomas,” Bone, vol. 43, no. 3, pp. 621–627, 2008. View at Publisher · View at Google Scholar · View at Scopus
  7. T. Mücke, F. Hölzle, S. Wagenpfeil, K.-D. Wolff, and M. Kesting, “The role of tumor invasion into the mandible of oral squamous cell carcinoma,” Journal of Cancer Research and Clinical Oncology, vol. 137, no. 1, pp. 165–171, 2011. View at Publisher · View at Google Scholar · View at Scopus
  8. C. K. Martin, J. L. Werbeck, N. K. Thudi et al., “Zoledronic acid reduces bone loss and tumor growth in an orthotopic xenograft model of osteolytic oral squamous cell carcinoma,” Cancer Research, vol. 70, no. 21, pp. 8607–8616, 2010. View at Publisher · View at Google Scholar · View at Scopus
  9. D. Ziech, I. Anestopoulos, R. Hanafi et al., “Pleiotrophic effects of natural products in ROS-induced carcinogenesis: the role of plant-derived natural products in oral cancer chemoprevention,” Cancer Letters, vol. 327, no. 1-2, pp. 16–25, 2012. View at Publisher · View at Google Scholar · View at Scopus
  10. D. Kavitha, P. N. Shilpa, and S. Niranjali Devaraj, “Antibacterial and antidiarrhoeal effects of alkaloids of Holarrhena antidysenterica Wall,” Indian Journal of Experimental Biology (IJEB), vol. 42, no. 6, pp. 589–594, 2004. View at Google Scholar · View at Scopus
  11. P. Jamadagni, S. Pawar, S. Jamadagni, S. Chougule, S. Gaidhani, and S. Murthy, “Review of Holarrhena antidysenterica (L.) Wall. ex A. DC.: Pharmacognostic, pharmacological, and toxicological perspective,” Pharmacognosy Reviews, vol. 11, no. 22, p. 141, 2017. View at Publisher · View at Google Scholar
  12. I. Gulcin, M. E. Buyukokuroglu, M. Oktay, and O. I. Kufrevioglu, “On the in vitro antioxidative properties of melatonin,” Journal of Pineal Research, vol. 33, no. 3, pp. 167–171, 2002. View at Publisher · View at Google Scholar · View at Scopus
  13. P. S. Ganapathy, Y. L. Ramachandra, and S. P. Rai, “In vitro antioxidant activity of Holarrhena antidysenterica Wall. methanolic leaf extract,” Journal of Basic and Clinical Pharmacology, vol. 2, no. 4, pp. 175–178, 2011. View at Google Scholar
  14. V. Sharma, S. Hussain, M. Bakshi, N. Bhat, and A. K. Saxena, “In vitro cytotoxic activity of leaves extracts of Holarrhena antidysenterica against some human cancer cell lines,” Indian Journal of Biochemistry and Biophysics, vol. 51, no. 1, pp. 46–51, 2014. View at Google Scholar · View at Scopus
  15. H.-J. Kim, J. Park, S. K. Lee, K. R. Kim, K.-K. Park, and W.-Y. Chung, “Loss of RUNX3 expression promotes cancer-associated bone destruction by regulating CCL5, CCL19 and CXCL11 in non-small cell lung cancer,” The Journal of Pathology, vol. 237, no. 4, pp. 520–531, 2015. View at Publisher · View at Google Scholar · View at Scopus
  16. M. Dizdaroglu, “Oxidatively induced DNA damage: mechanisms, repair and disease,” Cancer Letters, vol. 327, no. 1-2, pp. 26–47, 2012. View at Publisher · View at Google Scholar · View at Scopus
  17. I. R. Garrett, B. F. Boyce, R. O. C. Oreffo, L. Bonewald, J. Poser, and G. R. Mundy, “Oxygen-derived free radicals stimulate osteoclastic bone resorption in rodent bone in vitro and in vivo,” The Journal of Clinical Investigation, vol. 85, no. 3, pp. 632–639, 1990. View at Publisher · View at Google Scholar · View at Scopus
  18. D. A. Callaway and J. X. Jiang, “Reactive oxygen species and oxidative stress in osteoclastogenesis, skeletal aging and bone diseases,” Journal of Bone and Mineral Metabolism, vol. 33, no. 4, pp. 359–370, 2015. View at Publisher · View at Google Scholar · View at Scopus
  19. H. Y. Khan, H. Zubair, M. F. Ullah, A. Ahmad, and S. M. Hadi, “A prooxidant mechanism for the anticancer and chemopreventive properties of plant polyphenols,” Current Drug Targets, vol. 13, no. 14, pp. 1738–1749, 2012. View at Publisher · View at Google Scholar · View at Scopus
  20. A. J. León-González, C. Auger, and V. B. Schini-Kerth, “Pro-oxidant activity of polyphenols and its implication on cancer chemoprevention and chemotherapy,” Biochemical Pharmacology, vol. 98, no. 3, pp. 371–380, 2015. View at Publisher · View at Google Scholar
  21. G. I. Evan and K. H. Vousden, “Proliferation, cell cycle and apoptosis in cancer,” Nature, vol. 411, no. 6835, pp. 342–348, 2001. View at Publisher · View at Google Scholar · View at Scopus
  22. A. Gross, J. M. McDonnell, and S. J. Korsmeyer, “BCL-2 family members and the mitochondria in apoptosis,” Genes & Development, vol. 13, no. 15, pp. 1899–1911, 1999. View at Publisher · View at Google Scholar · View at Scopus
  23. J.-C. Martinou and D. R. Green, “Breaking the mitochondrial barrier,” Nature Reviews Molecular Cell Biology, vol. 2, no. 1, pp. 63–67, 2001. View at Publisher · View at Google Scholar · View at Scopus
  24. S. Chatterjee, G. Biswas, S. Chandra, G. K. Saha, and K. Acharya, “Apoptogenic effects of Tricholoma giganteum on Ehrlich's ascites carcinoma cell,” Bioprocess and Biosystems Engineering, vol. 36, no. 1, pp. 101–107, 2013. View at Publisher · View at Google Scholar · View at Scopus
  25. D. Vucic, V. M. Dixit, and I. E. Wertz, “Ubiquitylation in apoptosis: A post-translational modification at the edge of life and death,” Nature Reviews Molecular Cell Biology, vol. 12, no. 7, pp. 439–452, 2011. View at Publisher · View at Google Scholar · View at Scopus
  26. E. C. de Bruin and J. P. Medema, “Apoptosis and non-apoptotic deaths in cancer development and treatment response,” Cancer Treatment Reviews, vol. 34, no. 8, pp. 737–749, 2008. View at Publisher · View at Google Scholar · View at Scopus
  27. A. Sonnenblick, E. de Azambuja, H. A. Azim Jr., and M. Piccart, “An update on PARP inhibitors—moving to the adjuvant setting,” Nature Reviews Clinical Oncology, vol. 12, no. 1, pp. 27–41, 2015. View at Publisher · View at Google Scholar