Research Article

Wu-Mei-Wan Reduces Insulin Resistance via Inhibition of NLRP3 Inflammasome Activation in HepG2 Cells

Figure 5

Effects of WMW on mRNA expression of NLRP3 inflammasome in HepG2 cells. Control group is HepG2 cells in the normal state with no palmitate (PA) treatment. HepG2 cells were treated with serum without WMW (PA + N) or medicated serum containing low (PA + L), middle (PA + M), or high (PA + H) dose of WMW for 24 h. RT-qPCR results showed that the medicated serum of WMW increased the mRNA expression of IL-1β (a), NLRP3 (b), and caspase-1 (c). , , and .