Evidence-Based Complementary and Alternative Medicine

Research Article

Bark Extracts of Ceylon Cinnamon Possess Antilipidemic Activities and Bind Bile Acids In Vitro

Table 2

Cholesterol esterase inhibitory activity of bark extracts of Ceylon cinnamon and simvastatin.


Extract/Std	% inhibition					µg/mL
Extract/Std	Concentration (µg/mL)					µg/mL

Bark	3.125	6.25	12.5	25	50	IC₅₀

Ethanol	1.85 ± 0.58	12.49 ± 1.50	32.55 ± 0.32	48.65 ± 0.61	58.30 ± 1.12
DCM : M	2.44 ± 1.24	8.74 ± 0.29	27.47 ± 0.68	46.09 ± 0.58	57.99 ± 0.25

Std	2.5	5	10	20	30	IC₅₀

Simvastatin	18.49 ± 0.57	27.09 ± 1.16	34.38 ± 1.83	50.00 ± 3.33	73.75 ± 4.31

Data represented as mean ± SEM . Mean IC₅₀ values superscripted by different letters are significantly different at . Ethanol bark, DCM : M bark, and simvastatin are , 0.98, and 0.99, respectively. DCM : M: dichloromethane : methanol.