Research Article

Kyungheechunggan-Tang-01, a New Herbal Medication, Suppresses LPS-Induced Inflammatory Responses through JAK/STAT Signaling Pathway in RAW 264.7 Macrophages

Figure 7

KCT-01 has no inhibitory effect on activation of NF-κB or AP-1 in LPS-induced RAW264.7 macrophages. Cells were transfected with p-NF-κB-luc reporter or pAP-1-luc reporter. phRL-TK vector was used as an internal control. Cells were then treated with KCT-01 plus LPS or LPS alone. After 18 h of treatment, luciferase activity levels were determined using luciferase assay. Values are expressed as the means ± SD of three independent experiments. versus control.
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