Ficus hispida Bark Extract Prevents Nociception, Inflammation, and CNS Stimulation in Experimental Animal Model
Table 6
Effects of EFHB on carrageenan-induced oedema paw volume in Wistar rats.
Treatment
Dose (mg/kg)
Right hind paw volume (% inhibition)
1 h
2 h
3 h
4 h
5 h
Vehicle
10 (ml/kg)
1.03 ± 0.11
1.27 ± 0.16
1.38 ± 0.16
1.44 ± 0.19
1.58 ± 0.12
Indomethacin
10
0.48 ± 0.16 (53.22%
0.54 ± 0.19 (57.80%
0.54 ± 0.13 (60.76%
0.56 ± 0.18 (61.33%
0.51 ± 0.18 (67.72%
EFHB
100
0.82 ± 0.14 (19.69%
0.94 ± 0.14 (26.30%
0.98 ± 0.19 (29.07%
0.97 ± 0.15 (32.64%
1.02 ± 0.16 (35.44%
EFHB
200
0.76 ± 0.10 (25.54%
0.78 ± 0.22 (38.90%
0.84 ± 0.14 (39.24%
0.85 ± 0.11 (40.97%
0.87 ± 0.17 (44.94%
EFHB
400
0.55 ± 0.17 (46.60%
0.62 ± 0.18 (51.18%
0.66 ± 0.17 (52.17%
0.65 ± 0.21 (54.86%
0.64 ± 0.11 (59.49%
Here, each value is presented as the mean ± SEM . EFHB = ethanol extract of Ficus hispida. Indicating compared with control group (Dunnett’s test). Indicating compared with control group (Dunnett’s test).
