Poly-ε-Caprolactone Microsphere Polymers Containing Usnic Acid: Acute Toxicity and Anti-Inflammatory Activity

Figure 2

Liver sections of (a) control, (b) UA-micro (2000 mg/kg; p.o.), (c) UA (2000 mg/kg; p.o.), (d) UA (300 mg/kg; p.o.), and (e) UA (50 mg/kg; p.o.). S: hepatic sinusoids; HN: hepatocyte nucleus; HC: hepatic cell plates; CV: cytoplasmic vacuolation; II: inflammatory influx; CA: cytoplasmic acidophilia; CG: cytoplasmic granules (×400 magnification).

(a)

(b)

(c)

(d)

(e)