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Evidence-Based Complementary and Alternative Medicine
Volume 2017, Article ID 7593027, 12 pages
https://doi.org/10.1155/2017/7593027
Research Article

Components of Goutengsan in Rat Plasma by Microdialysis Sampling and Its Protection on Aβ1–42-Induced PC12 Cells Injury

1Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Shi Zi Street No. 100, Hongshan Road, Jiangsu, Nanjing 210028, China
2Key Laboratory of New Drug Delivery System of Chinese Materia Medica, Jiangsu Provincial Academy of Chinese Medicine, Shi Zi Street No. 100, Hongshan Road, Jiangsu, Nanjing 210028, China
3School of Pharmacy, Anhui University of Chinese Medicine, Hefei 230012, China
4School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China
5School of Traditional Chinese Medicine, China Pharmaceutical University, Nanjing 211198, China
6Jumpcan Pharmaceutical Co., Ltd., Taixing 225400, China

Correspondence should be addressed to Liang Feng; moc.361@ihsuixomnew

Received 1 December 2015; Revised 20 February 2016; Accepted 12 May 2016; Published 2 March 2017

Academic Editor: Helmut Hugel

Copyright © 2017 Hou-Cai Huang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. A. Farzan, S. Mashohor, A.-R. Ramli, and R. Mahmud, “Boosting diagnosis accuracy of Alzheimer's disease using high dimensional recognition of longitudinal brain atrophy patterns,” Behavioural Brain Research, vol. 290, pp. 124–130, 2015. View at Publisher · View at Google Scholar · View at Scopus
  2. W.-Y. Hsu, Y. Ku, T. P. Zanto, and A. Gazzaley, “Effects of noninvasive brain stimulation on cognitive function in healthy aging and Alzheimer's disease: a systematic review and meta-analysis,” Neurobiology of Aging, vol. 36, no. 8, pp. 2348–2359, 2015. View at Publisher · View at Google Scholar · View at Scopus
  3. A. Nakajima, Y. Aoyama, K. Yamada et al., “Nobiletin, a citrus flavonoid, improves cognitive impairment and reduces soluble Aβ levels in a triple transgenic mouse model of Alzheimer's disease (3XTg-AD),” Behavioural Brain Research, vol. 289, pp. 69–77, 2015. View at Publisher · View at Google Scholar · View at Scopus
  4. Y.-L. Zhang, C.-R. Lin, W.-S. Song et al., “Cognitive improvement during treatment for mild Alzheimer's disease with a Chinese herbal formula: a randomized controlled trial,” PLoS ONE, vol. 10, no. 6, Article ID e0130353, 2015. View at Publisher · View at Google Scholar · View at Scopus
  5. M. Bi, S. Tong, Z. Zhang et al., “Changes in cerebral glucose metabolism in patients with mild-to-moderate Alzheimer's disease: a pilot study with the Chinese herbal medicine fuzhisan,” Neuroscience Letters, vol. 501, no. 1, pp. 35–40, 2011. View at Publisher · View at Google Scholar · View at Scopus
  6. S.-J. Zhang and Z.-Y. Xue, “Effect of Western medicine therapy assisted by Ginkgo biloba tablet on vascular cognitive impairment of none dementia,” Asian Pacific Journal of Tropical Medicine, vol. 5, no. 8, pp. 661–664, 2012. View at Publisher · View at Google Scholar · View at Scopus
  7. P. N. Tariot, J. L. Cummings, I. R. Katz et al., “A randomized, double-blind, placebo-controlled study of the efficacy and safety of donepezil in patients with Alzheimer's disease in the nursing home setting,” Journal of the American Geriatrics Society, vol. 49, no. 12, pp. 1590–1599, 2001. View at Publisher · View at Google Scholar · View at Scopus
  8. P. Liu, M. Kong, S. Liu, G. Chen, and P. Wang, “All rights reserved effect of reinforcing kidney-essence, removing phlegm, and promoting mental therapy on treating Alzheimer's disease,” Journal of Traditional Chinese Medicine, vol. 33, no. 4, pp. 449–454, 2013. View at Publisher · View at Google Scholar · View at Scopus
  9. H. Watanabe, Q. Zhao, K. Matsumoto et al., “Pharmacological evidence for antidementia effect of Choto-san (Gouteng-san), a traditional Kampo medicine,” Pharmacology Biochemistry and Behavior, vol. 75, no. 3, pp. 635–643, 2003. View at Publisher · View at Google Scholar · View at Scopus
  10. H.-C. Huang, R.-L. Zhong, P. Cao, C.-R. Wang, and D.-G. Yang, “Effects of Goutengsan on model of alzheimer dementia in rats by AlCl3,” China Journal of Chinese Materia Medica, vol. 33, no. 5, pp. 553–556, 2008. View at Google Scholar
  11. K. Matsumoto, Q. Zhao, J.-I. Oka et al., “Kampo formulations, chotosan, and yokukansan, for dementia therapy: existing clinical and preclinical evidence,” Journal of Pharmacological Sciences, vol. 122, no. 4, pp. 257–269, 2013. View at Publisher · View at Google Scholar · View at Scopus
  12. Y.-R. Peng, H.-C. Huang, Y.-F. Ding, G.-T. Du, and X.-D. Liu, “The protection of Goutengsan in serum on PC12 cell injury,” Chinese Traditional Patent Medicine, vol. 28, pp. 1623–1625, 2006. View at Google Scholar
  13. Q. Zhang, D. Wu, J. Wu et al., “Improved blood-brain barrier distribution: effect of borneol on the brain pharmacokinetics of kaempferol in rats by in vivo microdialysis sampling,” Journal of Ethnopharmacology, vol. 162, pp. 270–277, 2015. View at Publisher · View at Google Scholar · View at Scopus
  14. B.-P. Carson, W.-G. McCormack, P.-M. Jakeman et al., “An in vivo microdialysis characterization of the transient changes in the interstitial dialysate concentration of metabolites and cytokines in human skeletal muscle in response to insertion of a microdialysis probe,” Cytokine, vol. 71, no. 2, pp. 327–333, 2015. View at Publisher · View at Google Scholar · View at Scopus
  15. E. Diczfalusy, M. Andersson, and K. Wårdell, “A diffusion tensor-based finite element model of microdialysis in the deep brain,” Computer Methods in Biomechanics and Biomedical Engineering, vol. 18, no. 2, pp. 201–212, 2015. View at Publisher · View at Google Scholar · View at Scopus
  16. R. A. Saylor and S. M. Lunte, “A review of microdialysis coupled to microchip electrophoresis for monitoring biological events,” Journal of Chromatography A, vol. 1382, pp. 48–64, 2015. View at Publisher · View at Google Scholar · View at Scopus
  17. M. Orłowska-Majdak, “Microdialysis of the brain structures: application in behavioral research on vasopressin and oxytocin,” Acta Neurobiologiae Experimentalis, vol. 64, no. 2, pp. 177–188, 2004. View at Google Scholar · View at Scopus
  18. L. Cao, G.-Z. Xin, X.-D. Wen, and P. Li, “Application of microdialysis and its hyphenated techniques in studies of traditional Chinese medicines,” Chinese Journal of New Drugs, vol. 21, no. 6, pp. 605–610, 2012. View at Google Scholar · View at Scopus
  19. P. Meng, H. Yoshida, K. Tanji et al., “Carnosic acid attenuates apoptosis induced by amyloidβ 1-42 or 1-43 in SH-SY5Y human neuroblastoma cells,” Neuroscience Research, vol. 94, pp. 1–9, 2015. View at Publisher · View at Google Scholar · View at Scopus
  20. N. M. Hooper and J. V. Rushworth, “Lipid rafts: linking Alzheimer's amyloid-β production, aggregation, and toxicity at neuronal membranes,” International Journal of Alzheimer's Disease, vol. 2011, Article ID 603052, 14 pages, 2011. View at Publisher · View at Google Scholar · View at Scopus
  21. M. E. Larson and S. E. Lesné, “Soluble Aβ oligomer production and toxicity,” Journal of Neurochemistry, vol. 120, no. 1, pp. 125–139, 2012. View at Publisher · View at Google Scholar · View at Scopus
  22. F. Heti, W.-F. Goure, G.-A. Krat et al., “The case for soluble A oligomers as a drug target in Alzheimer's disease,” Trends in Pharmacological Sciences, vol. 34, pp. 261–266, 2013. View at Google Scholar
  23. M.-C. Qian, J. Liu, J.-S. Yao et al., “Caspase-8 mediates amyloid-β-induced apoptosis in differentiated PC12 cells,” Journal of Molecular Neuroscience, vol. 56, no. 2, pp. 491–499, 2015. View at Publisher · View at Google Scholar · View at Scopus
  24. T.-T. Rohn, “The role of caspases in Alzheimer's disease: potential novel therapeutic opportunities,” Apoptosis, vol. 15, no. 11, pp. 1403–1409, 2010. View at Publisher · View at Google Scholar · View at Scopus
  25. R. Tamayev, N. Akpan, O. Arancio, C.-M. Troy, and L. D'Adamio, “Caspase-9 mediates synaptic plasticity and memory deficits of Danish dementia knock-in mice: caspase-9 inhibition provides therapeutic protection,” Molecular Neurodegeneration, vol. 7, article 60, pp. 1–11, 2012. View at Publisher · View at Google Scholar · View at Scopus
  26. M. L. Würstle, M. A. Laussmann, and M. Rehm, “The central role of initiator caspase-9 in apoptosis signal transduction and the regulation of its activation and activity on the apoptosome,” Experimental Cell Research, vol. 318, no. 11, pp. 1213–1220, 2012. View at Publisher · View at Google Scholar · View at Scopus