Research Article

Optimized-SopungSunkiwon, a Herbal Formula, Attenuates Aβ Oligomer-Induced Neurotoxicity in Alzheimer’s Disease Models

Figure 2

Inhibitory effect of OSS on -induced NO generation in BV-2 microglial cells. The cells were with 1 μM 1 h after OSS treatment (a) or 1 h before OSS treatment (b). NO generation was determined by the nitrite level in the supernatant using the Griess reagent. OSS pre- or posttreatment inhibited overproduction of nitrite level by stress. Values are indicated as the mean ± SEM. 1 compared to the control group; compared to the -only treated group.