Research Article

Lannea acida A. Rich. (Anacardiaceae) Ethanol Extract Exhibits Estrogenic Effects and Prevents Bone Loss in an Ovariectomized Rat Model of Osteoporosis

Table 3

Effects of the ethanol extract of Lannea acida on estrogen target organs in postmenopausal-rat model after 12 weeks of treatment.

ItemsShamOvariectomized rats
OVXE2VLannea acida (mg/kg BW)
50200

Uterine wet weight (mg/kg)
Uterine epithelial height (µm)
Vaginal epithelial height (µm)

Sham (sham operated) and OVX (ovariectomized) animals received the vehicle (distilled water); E2V = OVX animals treated with 1 mg/kg of 17β-estradiol valerate; Lannea acida = OVX animals treated with ethanol extract of Lannea acida at doses of 50 and 200 mg/kg BW. Data are expressed as mean ± SEM (); and as compared to the OVX group. as compared to the Sham group.