Lannea acida A. Rich. (Anacardiaceae) Ethanol Extract Exhibits Estrogenic Effects and Prevents Bone Loss in an Ovariectomized Rat Model of Osteoporosis

Table 5

Effects of Lannea acida ethanol extract after 12 weeks of oral treatment in some biomarkers of osteoporosis.

Items	Sham	Ovariectomized rats
		OVX	E2V	Lannea acida (mg/kg BW)
				50	200
Alkaline phosphatase (UI/L)
Calcium (mmol/L)
Tibia
Femur
Inorganic phosphorus (mmol/L)
Tibia
Femur

Sham (sham operated) and OVX (ovariectomized) animals received the vehicle (distilled water); E2V = OVX animals treated with 1 mg/kg of estradiol valerate; Lannea acida = OVX animals treated with ethanol extract of Lannea acida at doses of 50 and 200 mg/kg BW. Data are expressed as mean ± SEM (); and as compared to the OVX group.