Lannea acida A. Rich. (Anacardiaceae) Ethanol Extract Exhibits Estrogenic Effects and Prevents Bone Loss in an Ovariectomized Rat Model of Osteoporosis

Table 6

Effects of Lannea acida ethanol extract on hematological parameters after 11 weeks of treatment in postmenopausal-rat model.

Items	Normal ranges	Sham	Ovariectomized rats
			OVX	E2V	Lannea acida (mg/kg BW)
					50	200
WBC (10^3/μL)	5–16
Lymphocytes (%)	65–85
Monocytes (%)	0–20
Granulocytes (%)	0–27
RBC (10^6/μL)	5–10
Hematocrit (%)	32–53
Hemoglobin (g/dL)	12–18
MCV (fL)	52–60
MCH (pg)	17–29
MCHC (g/dL)	32–45
Platelets (10^3/μL)	200–1100

Sham (sham operated) and OVX (ovariectomized) animals received the vehicle (distilled water); E2V = OVX animals treated with 1 mg/kg of 17β-estradiol valerate; Lannea acida = OVX animals treated with ethanol extract of Lannea acida at doses of 50 and 200 mg/kg BW. Data are expressed as mean ± SEM (); and as compared to the OVX group.