Schisandra chinensis and Morus alba Synergistically Inhibit In Vivo Thrombus Formation and Platelet Aggregation by Impairing the Glycoprotein VI Pathway

Figure 6

SCC + MAL reduced the phosphorylation of MAPK (i.e., ERK1/2 and JNK but not p38) and Akt. Cell proteins were extracted after aggregation was terminated, and proteins were separated using SDS-PAGE, transferred to PVDF membranes, and then probed with antibodies against total and phospho-ERK1/2, JNK, p38, and Akt. All immunoblots were carried out in at least four independent experiments. and compared to the agonist-treated group.