|
| Parameter | Placebo () | PGD () | |
|
| Age (years) | 28.55 ± 5.24 (25.28–31.12) | 28.42 ± 3.95 (26.95–29.36) | 0.93 |
| Duration of the illness (months) | 16.75 ± 8.30 (11.72–20.41) | 17.14 ± 7.15 (15.57–20.11) | 0.87 |
| Number of psychotic relapses | 8 (40%) | 9 (42.9%) | 0.8 |
| Amisulpride treatment duration (months) | 6.6 ± 3.28 (4.50–6.96) | 7.09 ± 2.36 (6.54–8.08) | 0.58 |
| Amisulpride dosage | 0.88 ± 0.24 (0.78–1.04) | 0.85 ± 0.26 (0.76–0.92) | 0.78 |
| Hyperprolactinemia-related symptoms | | | 0.98 |
| Amenorrhea | 5 (25%) | 5 (23.8%) | |
| Abnormal menstruation | 5 (25%) | 4 (19%) | |
| Galactorrhea | 4 (20%) | 5 (23.8%) | |
| Reduced libido | 4 (20%) | 4 (19%) | |
| Sexlessness | 2 (10%) | 3 (14.3%) | |
| PRL (ng/mL) | 46.25 ± 5.43 (43.08–48.78) | 47.62 ± 5.16 (45.63–48.90) | 0.41 |
| Hormone assays | | | |
| Estradiol (pg/mL) | 54.25 ± 27.98 (37.53–73.14) | 59.67 ± 26.21 (49.55–66.87) | 0.53 |
| Progesterone (ng/mL) | 16.10 ± 4.01 (13.77–17.43) | 16.57 ± 3.59 (15.41–17.54) | 0.69 |
| FSH (IU/L) | 14.75 ± 3.80 (13.60–17.74) | 13.52 ± 2.82 (12.53–14.41) | 0.25 |
| LH (IU/L) | 27.15 ± 10.62 (22.45–28.03) | 23.43 ± 6.48 (20.72–24.96) | 0.19 |
| Initial PANSS score | 50.45 ± 4.04 (48.45–52.88) | 52.76 ± 4.65 (51.12–54.24) | 0.08 |
| Positive subscale | 19.85 ± 3.95 (18.22–21.38) | 20.52 ± 3.31 (19.12–21.20) | 0.60 |
| Negative subscale | 12.00 ± 3.34 (10.87–14.06) | 13.71 ± 3.68 (12.55–15.03) | 0.09 |
| General subscale | 18.60 ± 2.64 (16.95–19.84) | 18.52 ± 4.48 (17.23–20.24) | 0.95 |
| Biochemical indexes | | | |
| ALT (U/L) | 33.85 ± 12.93 (27.03–42.17) | 36.33 ± 10.46 (32.06–38.99) | 0.50 |
| AST (U/L) | 29.55 ± 10.67 (25.44–37.49) | 33.52 ± 7.68 (30.39–34.87) | 0.18 |
| BUN (mmol/L) | 5.47 ± 2.26 (4.61–7.15) | 5.34 ± 1.51 (4.78–5.78) | 0.83 |
| CRE (μmol/L) | 69.24 ± 15.09 (60.98–79.78) | 68.77 ± 10.66 (64.18–70.83) | 0.91 |
| TG (mmol/L) | 2.92 ± 1.70 (2.04–3.96) | 2.89 ± 1.51 (2.24–3.17) | 0.95 |
| GLU (mmol/L) | 4.76 ± 0.76 (4.26–5.00) | 4.98 ± 0.68 (4.74–5.19) | 0.32 |
| TSH (uIU/mL) | 6.45 ± 2.36 (5.14–8.07) | 7.73 ± 1.75 (7.08–8.27) | 0.054 |
|
