Huanglian-Jie-Du-Tang Extract Ameliorates Depression-Like Behaviors through BDNF-TrkB-CREB Pathway in Rats with Chronic Unpredictable Stress

Figure 3

The effect of HJDT on the sucrose consumption ratio in SPT after the CUS. The sucrose consumption ratio decreased in the CUS depression group. Treatment with paroxetine and HJDT (2, 4 g/kg) increased the sucrose consumption ratio. relative to the normal control group; and relative to the CUS depression group. N: normal control group; D: CUS depression group; P: paroxetine group; HJDT 2: HJDT 2 g/kg group; HJDT 4: HJDT 4 g/kg group; HJDT 8: HJDT 8 g/kg group.