Icariin Regulates the Bidirectional Differentiation of Bone Marrow Mesenchymal Stem Cells through Canonical Wnt Signaling Pathway

<div>Icariin inhibits OVX-induced bone loss. (a) Images of the distal femurs were obtained after 6-week intervention (top, coronal view of the metaphyseal region; middle, sagittal view; bottom, transverse view). (b) Analysis of the parameter of the three-dimensional trabecular structure of the distal femur: BV/TV: trabecular bone volume/tissue volume; Tb.N: trabecular number; Tb.Sp: trabecular separation; Tb.Th: trabecular thickness. 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Evidence-Based Complementary and Alternative Medicine

fig1

Figure 1

Figure 1: Icariin Regulates the Bidirectional Differentiation of Bone Marrow Mesenchymal Stem Cells through Canonical Wnt Signaling Pathway 