Research Article

Astilbin from Smilax glabra Roxb. Attenuates Inflammatory Responses in Complete Freund’s Adjuvant-Induced Arthritis Rats

Figure 4

Astilbin treatment reduced proinflammatory cytokine production. (a) The mRNA expression of TNF-α, IL-1β, and IL-6 in the synovium from rats was examined by real-time PCR. (b) Serum cytokine levels of TNF-α, IL-1β, and IL-6 in rats were determined by PicoKine ELISA Kit (BosterBio, Wuhan, China). Data shown represent the mean ± SD of three independent experiments, rats per group as described in Materials and Methods. , versus control group; , , versus CFA-induced arthritic rat model group.