Renoprotective Effects of Total Glucosides from Paeony against Nephrotoxicity Induced by Total Alkaloids from Semen Strychni

Table 1

Precision, accuracy, recovery, and matrix effect of HPLC-MS method for analysis of analytes and IS ().

Analytes	C (ng/mL)	Intraday	Interday	Accuracy	Recovery	Matrix effect
		(RSD%)	(RSD%)	(RE%)	(%, mean ± SD)	(%, mean ± SD)
Strychnine	15	13.0	10.3	−15.4	81.1 ± 5.6	92.5 ± 6.8
	140	7.5	7.9	9.1	95.4 ± 4.3	93.4 ± 6.4
	300	4.6	6.5	4.8	91.9 ± 5.3	88.3 ± 5.6
Brucine	15	11.8	10.0	−14.7	82.2 ± 12.6	87.5 ± 6.4
	50	6.1	5.3	6.1	92.2 ± 4.7	104.6 ± 5.2
	80	3.6	4.9	3.5	91.8 ± 8.2	99.3 ± 4.2