Antioxidant, Anti-Inflammatory, and Analgesic Activities of Agrimonia eupatoria L. Infusion

Table 3

Effect of AePFD3 on the time that mice spent licking their hind paw during early and late phase of formalin test.

Group	Dose; (mg/kg)	Time spent licking (0–5 min)	Time spent licking (20–40 min)	Pain reduction (%)
Control	—			—
Reference	10			98.4
AePFD3	72.48			32.5

Reference: morphine hydrochloride (10 mg/kg b.w.) for early phase or diclofenac sodium (10 mg/kg b.w.) for late phase; AePFD3: ethyl acetate fraction of the aqueous extract at dose 72.48 mg/kg b.w. Each value is the mean ± SEM of 6–8 rats. Statistical differences between the treated and the control groups were determined by ANOVA followed by Tukey’s test. compared with control.