In Vivo Subacute Toxicity and Antidiabetic Effect of Aqueous Extract of Nigella sativa
Table 4
Two-way ANOVAs testing the effects of rat treatments: “Groups,” treatment duration “Time,” and their interaction “Groups × Time” on the variation of serum biochemical parameters in Rattus norvegicus.
Parameters
Groups of rats
Time
Groups × Time
Glycemia
76.56
<0.001
11.94
<0.001
12.67
<0.001
Triglycerides
6.35
0.005
6.07
0.002
2.36
0.056
T-Cholesterol
5.18
0.012
4.10
0.015
3.54
0.009
HDL-c
5.87
0.008
3.16
0.041
3.15
0.018
LDL-c
11.39
<0.001
11.25
<0.001
21.12
<0.001
Insulinemia
0.29
0.749
5.05
0.013
0.90
0.477
TBARS in sera
1.29
0.291
7.99
0.001
1.95
0.108
TBARS in erythrocytes
0.96
0.394
0.72
0.549
1.19
0.341
AST
1.75
0.190
1.32
0.287
0.82
0.565
ALT
16.01
<0.001
0.55
0.650
8.18
<0.001
F: F-statistics; : value. Difference is significant when .
