Research Article
Acupuncture Improved Neurological Recovery after Traumatic Brain Injury by Activating BDNF/TrkB Pathway
Figure 3
The phosphorylation of downstream molecular BDNF/TrkB signaling pathway was significantly increased in acupuncture-treated rats had been persistently enhanced after TBI. The phosphorylated Akt at 12 h, 48 h, 96 h, and 168 h after TBI was examined by western blot (a) and immunohistochemistry (e). (b) is the quantitative analysis of (a). The phosphorylated Erk1/2 at 12 h, 48 h, 96 h, and 168 h after TBI was examined by western blot (c) and immunohistochemistry (f). (e) is the quantitative analysis of (d). The phosphorylated PLCγ1 at 12 h, 48 h, 96 h, and 168 h after TBI was examined by western blot (g). (h) is the quantitative analysis of (g). Scale bar, 50 m. Acu: acupuncture. and versus TBI group.
(a) |
(b) |
(c) |
(d) |
(e) |
(f) |
(g) |
(h) |