Acupuncture Improved Neurological Recovery after Traumatic Brain Injury by Activating BDNF/TrkB Pathway

Figure 5

Blocking BDNF/TrkB pathway significantly prevented acupuncture-induced amelioration of cognitive impairment. The rats were trained to remember the hidden platform in the maze from 14 to 19 days after TBI (a). The platform was removed at 21 days, then the time stayed in the target quadrant (b), and the number of crossing platform (c) were examined. (d–f) LTP measurements were performed at 21 days after TBI. Normalized excitatory postsynaptic potential (EPSP) slope (d) and population spike (PS) amplitude (e) were measured. and versus TBI group; versus TBI + Acu group.

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