Fraction n-Butanol of Radix Notoginseng Protects PC12 Cells from A<i>β</i><sub>25–35</sub>-Induced Cytotoxicity and Alleviates Cognitive Deficits in SAMP8 Mice by Attenuating Oxidative Stress and A<i>β</i> Accumulation

<div>Effect of fraction NB on learning and memory abilities of SAMP8 in the MWM test. After treatment with different concentrations of fraction NB, the learning and memory abilities of SAMP8 mice were detected using MWM. ((a) and (b)) The average escape latency and percentage of time in the target quadrant of four-day training, respectively. (c) The percentage of time spent in the target quadrant of each mouse on day 5. Data in each experiment represent mean ± SD from 10–12 independent samples. 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Evidence-Based Complementary and Alternative Medicine

fig3

Figure 3

Figure 3: Fraction n-Butanol of Radix Notoginseng Protects PC12 Cells from A<i>β</i><sub>25–35</sub>-Induced Cytotoxicity and Alleviates Cognitive Deficits in SAMP8 Mice by Attenuating Oxidative Stress and A<i>β</i> Accumulation 

Figure 3 | Fraction n-Butanol of Radix Notoginseng Protects PC12 Cells from Aβ25–35-Induced Cytotoxicity and Alleviates Cognitive Deficits in SAMP8 Mice by Attenuating Oxidative Stress and Aβ Accumulation 