The Anti-Inflammatory Effect of Guchangzhixie-Pill by Reducing Colonic EC Cell Hyperplasia and Serotonin Availability in an Ulcerative Colitis Rat Model

Figure 4

Representative Fontana-Masson stained sections of colonic EC cells specimens harvested from the control rats (a), from the TNBS-induced UC rats (b), from the TNBS-induced UC rats given pCPA (c), and from the TNBS-induced UC rats given GCZX-pill 9.6 g/kg (d), scale bar = 20 μm; the EC cells are indicated by arrows. Statistical graph of EC cell density is shown in (e). Representative western blot analysis figure of colonic TPH expression (relative to beta-actin) is shown in (f). Statistical graph of quantified optical density is shown in (g). Data are shown as mean ± SEM ( = 12 per group). < 0.01 versus the control rats; < 0.05 and < 0.01 versus the UC rats; one-way ANOVA followed by Bonferroni’s posttest.

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