The Anti-Inflammatory Effect of Guchangzhixie-Pill by Reducing Colonic EC Cell Hyperplasia and Serotonin Availability in an Ulcerative Colitis Rat Model

Figure 5

The effect of GCZX-pill on colonic 5-HT content in TNBS-induced UC rats is shown in (a). Representative immunohistochemical micrographs of colonic SERT expression specimens harvested from the control rats (b), from the TNBS-induced UC rats (c), and from the TNBS-induced UC rats given GCZX-pill 9.6 g/kg (d), scale bar = 50 μm. Statistical graph of SERT expression is shown in (e). Data are shown as mean ± SEM ( = 12 per group). < 0.01 versus the control rats; < 0.05 and < 0.01 versus the UC rats; one-way ANOVA followed by Bonferroni’s posttest.

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