Review Article

Potential of Traditional Knowledge of Plants in the Management of Arthropods in Livestock Industry with Focus on (Acari) Ticks

Table 3

An enumeration of plant species that have been documented in literature to contain compounds and/or active ingredients that have effects on livestock ticks worldwide.

Species name of plant (English name)Family name of plantPart(s) of plant usedApplication form/action (effects) and target tick speciesPlaceSource/
Reference

Acalypha fruticosa Forssk. Var. Villosa HutchEuphorbiaceae (spurge family) LeafSediment smeared onto the ears as repellent against ticks by the Turkana people of Kenya (aqueous preparation) eteteleit (Turkana language)Kenya[67]
As tick attractant as observed in the field and laboratory (Luo, Abaki)Kenya[122]

Acorus calamus L.Araceae (arum/ginseng family)RhizomeRepellent (aqueous and alcohol extracts) against Ixodes spp.USA[18, 123, 124]

Allium sativum (Link.) Döll. (Garlic)Alliaceae (onion family)Leaf/bulbEat garlic pills, tick repellent against Ixodes spp.Mecklenburg County, North Carolina, USA[125]

Ageratum houstonianum P. Mill. (Blue Mink)Compositae/Asteraceae (daisy/aster family)Essential oil from flowersToxic to ticks (Rhipicephalus lunulatus) at LD50 = 0.06653 µl/cm2 within 24 hrs.Cameroon[126]

Aloe broomii Schonl.XanthorrhoeaceaeLeafBoiling in water to make cattle dip and disinfectant. Oral leaf juice is made for cattle or for topical applicationSouth Africa; Kenya[67, 127]

Aloe ferox Mill. (cape aloe, bitter aloe, red aloe, and tap aloe)XanthorrhoeaceaeLeafInfusion had a strong dipping and topical toxicity effect against Rhipicephalus appendiculatus ticksSouth Africa[128]

Aloe marlothii Alwin Berger (mountain aloe or the flat-flowered aloe)XanthorrhoeaceaeLeafDichloromethane extracts were repellent to Rhipicephalus appendiculatusSouth Africa[128]

Aloe spp.XanthorrhoeaceaeLeafTopical application of a paste of leaves, paraffin oil, and kitchen ashKenya[67]

Aloe secundiflora Engl. (aloe)XanthorrhoeaceaeWhole plantA concoction mixed with labia plant (Psiadia punctulata) to make an effective acaricide against brown ear tick (Rhipicephalus appendiculatus), red-legged tick (Rhipicephalus evertsii evertsi), Boophilus decoloratus, and bont tick (Amblyomma species)Kenya (Samburu pastoralists) in Baragoi[129]

Andropogon gayanus Kunth (bluestem, gamba, or llanero grass)Poaceae or Gramineae (the grass family)Whole plantToxic/repellentSouth America, Mexico, Colombia[108, 130134]

Annona squamosa L. (sugar apple, custard apple, and sweetsop)Annonaceae (custard apple family)LeafLeaves rubbed over floors or placed in hens’ nests to keep away vermin which includes ticksIndia and Mexico[135]

Artocarpus altilis (Parkinson) Fosberg (breadfruit)Moraceae (fig/mulberry family)Fresh leafTopical application of crude ethanol extracts/being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst.Jamaica[58, 136, 137]

Asclepias curassavica L. (redhead)Asclepiadaceae (milkweed family)Fresh leafTopical application of crude ethanol extracts/being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst.Jamaica[58]

Artemisia absinthium L. (wormwood)AsteraceaeWhole plantEssential oils from the plant have been shown to have acaricidal activityEurope, Eastern North America[137] http://www.florahealth.com/about_int.cfm?sub_link=Export

Artemisia herba-alba Asso (white wormwood)AsteraceaeAerial partsDiethyl ether, ethyl acetate, hexane, and ethanol extracts showed toxicity against larvae of Hyalomma dromedarii Koch, 1844Egypt[138]

Artemisia tridentata Nutt. (big sagebrush)AsteraceaeLeavesToxic to nymphal ticks (Ixodes scapularis (Say)) (LC50 = 0.180% wt : vol)USA[139]

Artemisia monosperma Del. (Tarragon)AsteraceaeAerial partsDiethyl ether, ethyl acetate, hexane, and ethanol extracts showed toxicity against larvae of Hyalomma dromedarii Koch, 1844. Essential oils showed toxicity effects to the larvae of H. dromedarii and Argas persicus Oken, 1818, adultsEgypt[138]

Azadirachta indica Adr. Juss. (neem tree)Meliaceae (mahogany family) Whole plant; leaf; fruitRepellent/toxic/inhabitant of oviposition and embryogenesis of Boophilus microplus Canst.Kenya
Jamaica
[67, 140]
[58, 136]
FruitOil extracts caused mortality of Amblyomma variegatum larvaeNigeria[141]
Neem seed oil extracts caused mortality of Hyalomma anatolicum excavatum Koch larvae and malformation or deformities in developing ticksEgypt[142]
Neem oil and azadirachtin EC formulationAt 2500 mg litre−1, azadirachtin caused significant reduction in feeding activity of larva (Hyalomma dromedarii), prolonged the period for molting to nymphal stage, and caused 60% reduction in moltability. Contact and dipping LC50 values were >40.7 µg cm−2 and >5000 mg litre−1, respectively.Saudi Arabia[143]
SeedNeem seed oil as an acaricideIndia[144]
SeedNeem seed oil as an acaricide against Boophilus microplusIndia[145, 146]
SeedNeem seed extracts as acaricide against Boophilus microplusColombia[147]

Bixa orellana L. (annatto)Bixaceae (achiote/annatto/lipstick tree family)Fresh leafTopical application of crude ethanol extracts/being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplusJamaica[58]

Blighia sapida (ackee, akee, or achee)Sapindaceae (soapberry family)Fresh leafTopical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplusJamaica[58]

Bocconia frutescens L. (tree celandine/parrotweed/plume
poppy)
Papaveraceae (poppy family)Fresh leafTopical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplusJamaica[58]

Bontia daphnoides L. (kidney bush/white alling)Myoporaceae (Lamiales)Fresh leafTopical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplusJamaica[58]

Boscia angustifolia A. RichCapparidaceaeAerial parts/oilRepellency of their essential oilKenya[104]

Boscia mossambicensis KlotzschCapparidaceaeAerial parts/oilRepellency of their essential oilKenya[104]

Brachiaria brizantha (Hochst) Stapf cv. Marandu (marandu grass, surinam grass, signal grass, and Kenya sheep grass)GramineaeWhole plantAntitick propertiesSouth America, Brazil[131]

Brachiaria decumbens (signal grass)Grass family PanicoideaeWhole plantWeak toxic/repellentSouth America[108]

Cadaba farinosa Forssk.CapparidaceaeAerial parts/oilRepellency of their essential oilKenya[104]

Cadia purpurea (G. Piccioli) AitonCaesalpiniaceaeWhole plantA concoction mixed with Olea europaea subsp. Cuspidata (African olive tree) to make effective acaricide against brown ear tick (Rhipicephalus appendiculatus), red-legged tick (Rhipicephalus evertsii evertsii), Boophilus decoloratus, and bont tick (Amblyomma species)Kenya (Samburu pastoralists) in Baragoi[129]

Calocedrus decurrens (incense cedar and California post cedar)Cupressaceae (cypress family)Ground heartwood and leavesToxic to nymphal and larval ticks (Ixodes scapularis (Say)) (LC50 = 0.343 and 0.015% wt : vol, resp.)USA[139]

Calotropis procera (Ait) R. Br. (rooster tree, giant milkweed, and sodom apple)Asclepiadaceae (milkweed family)A cardiac glycosidal (cardenolide) extractContact and dipping LC50 values were 9.63 µg cm−2 and 1096 mg litre−1, respectively, against Hyalomma dromedarii larvaeSaudi Arabia[143]
LatexFound to be acaricidalEgypt[148]

Calpurnia aureaFabaceae/Papilionaceae/Leguminosae (Hardy annual legume/pea family)Leaf and barkJuice mixed with spice of Capsicum spp.Ethiopia[149]

Cinnamomum camphora (camphor plant)Lauraceae 
The Laurel family
Acaricide, essential oils repellent against Ixodes spp.USA[150]

Cannabis sativa L.(ganja/marijuana, marihuana, hemp, hashish, pot)Cannabaceae (hemp family)Fresh leafTopical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst.Jamaica[58]

Capsicum annum L.(scotch bonnet/pimento or sweet pepper)Solanaceae (lemon pepper/nightshade/potato family)Fresh leafTopical application of crude ethanol extracts. Being Toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst.Jamaica[58]

Capsicum spp.Solanaceae (lemon pepper/nightshade/potato family)Fruits/leavesSpice mixed with juice of leaf and bark from Calpurnia aurea to form an acaricideEthiopia[149]

Calpurnia aurea L.Fabaceae/Papilionaceae/Leguminosae/
Papilionaceae (hardy annual, legume/pea/bean family)
Leaf and barkSpice mixed with juice of leaf and bark from Calpurnia aurea to form an acaricideEthiopia[149]

Carduus leptacanthus Fresen.Asteraceae (also known as Compositae or daisy family)AcaricideRwanda[151]

Cassia tora L.Caesalpiniaceae/Leguminosae/
Papilionaceae/Fabaceae (hardy annual, legume bean/pea family)
LeafJuice of smashed leaves orallyIndia[152]

Cassia occidentalis L./Senna occidentalis L. (coffee senna/coffeeweed)Caesalpiniaceae/Leguminosae/
Papilionaceae/Fabaceae, (Hardy annual – legume Bean/pea Family)
Fresh leafTopical application of crude ethanol extracts. Being toxic and inhabitant of oviposition of Boophilus microplus Canst.Jamaica[58]

Catharanthus roseus L. (Madagascar periwinkle)Apocynaceae (dogbane family)Fresh leafTopical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst.Jamaica[58]

Cecropia peltata L. (trumpet tree)Cecropiaceae (previously included in the family Moraceae, mulberry family)Fresh leafTopical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst.Jamaica[58]

Cenchrus ciliaris L. (buffel grass)Poaceae (the grass family)Whole plantRepellentSouth America[113]

Chamaecyparis lawsoniana (A. Murr.) Parl. (Port Orford cedar)Cupressaceae (cypress family)Stump oilToxic to nymphal and larval ticks (Ixodes scapularis (Say)) (LC50 = 0.487 and 0.041% wt : vol, resp.)USA[139]

Chamaecyparis nootkatensis (D. Don) Spach (Alaska yellow-cedar)Cupressaceae (cypress family)Heartwood and leavesToxic to nymphal and larval ticks (Ixodes scapularis (Say)) (LC50 = 0.151 and 0.007% wt : vol, resp.)USA[139]

Chebliswo-plant in Pokot vernacular in KenyaRoot and LeafSolution of smashed partsKenya[153]

Chenopodium ambrosioides L. Mexican teaChenopodiaceae (goose-foot family)Rwanda[151]

Chenopodium ugandaeChenopodiaceae (goose-foot family)Uganda[151]

Chrysanthemum cinerariaefolium L.Asteraceae (also known as Compositae or daisy family)FlowersPyrethrins act as acaricide/toxicant/repellentUSA[150]

Citronella plantsMyrtaceae (Poaceae or Gramineae)LeafExtracts-tick repellents against Ixodes spp.USA[154]

Citrullus lanatus Thunb.Cucurbitaceae (cucumber family)FruitZimbabwe[18, 105]

Citrus aurantium L.(Seville orange)Rutaceae (rue family)Fresh leafTopical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst.Jamaica[58]

Cleome hirta (Klotzsch.) Oliv.CleomaceaeAerial parts/oilRepellent/toxic/killer of ticks (Rhipicephalus appendiculatus)Kenya[155]

Cleome gynandra (Cleome)CleomaceaeLeavesRepellents and acaricides for certain larval, nymphal, and adult ticksSouth Africahttp://www.daff.gov.za/docs/brochures/cleome.pdf

Clerodendrum glabrum E. Mey.LamiaceaeLeafAcetone extracts showed relatively high repellency activity against Rhipicephalus appendiculatus ticksSouth Africa[128]

Commiphora swynnertonii Burtt.Burseraceae (copal family and/or torchwood family)Gum resinRepellency of their essential oilKenya[104]

Commiphora erythraea Engler.Burseraceae (copal family and/or torchwood family)Gum resin/viscous oil/pure components/hexane extractSmear paste of camel urine and gum resin/toxic/repellent/larvicideKenya[67, 116, 156, 157]

Commiphora holtzianaBurseraceae (copal family and/or torchwood family)Gum, bark, and leafRepellentKenya[117]

Commiphora incisaBurseraceae (copal family and/or torchwood family)Gum resinSmear paste of camel urine and gum resinKenya[67]

Commiphora merkeri Engl.Burseraceae (copal family and/or torchwood family)Gum, bark, and leafAcaricide[158]

Commiphora myrrh Jacq. (Commiphora abyssinica (Nees) Engl., Commiphora myrrha (Nees) Engl., and Commiphora schimperi (Nees) Engl.) (all these plants are sources of Myrrh)Burseraceae (copal family and/or torchwood family)Gum resin/oil/pure componentsToxic/RepellentKenya[116, 156]
Oleoresin gum (crude myrrh)Myrrh essential oil/oil of Heerabol Myrrh (bola, myrrha and gum, common, and hirabol myrrh), repellent against Ixodes spp.Mecklenburg County, North Carolina, USA[125]

Commiphora molmol Engler.Burseraceae (copal family and/or torchwood family)MyrrhLC50 of Myrrh extract caused death of fowl tick Argas persicus by destroying the epithelial gut of cellsEgypt[159]

Commiphora tenuisBurseraceae (copal family)Larger leafToxic/repellent when rubbed on camels’ coatsKenyaWanzala-Personal experience with Somali pastoralists

Crotalaria retusa L. (rattle weed)Caesalpiniaceae/Leguminosae/Papilionaceae/
Fabaceae, (Hardy annual, legume bean/pea family)
Fresh leafTopical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst.Jamaica[58]

Cuscuta americana L. (love bush/weed)Cuscutaceae (Convolvulaceae) (dodder family)Fresh leafTopical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst.Jamaica[58]

Cycloptis semicordata L. (tall fern)Polypodiaceae (polypody/fern family)Fresh leafTopical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst.Jamaica[58]

Cymbopogon flexuosus (Nees ex Stend.) Wats. (lemon grass)Gramineae (Poaceae) (grass family)LeafA blend with marjoram grass and tea tree essential oils forms antitick repellent sprayNew Zealand[160]

Cymbopogon martinii stapf var. motia/(Roxb.) Wats. var. motia Burk.Gramineae (Poaceae) (grass family)
Leaf/flowerPalmarosa essential oil (Turkish Geranium/Andropogon/Nepal), tick repellent against Ixodes spp.Mecklenburg County, North Carolina, USA[125]

Cymbopogon nardus R. (Andropogon nardus) (citronella grass, lemon grass, nardus)Gramineae (Poaceae) (grass family)Leaf/flowerCitronella essential oil (lemon balm, Sri Lanka or Lenabatu citronella), tick repellent against Ixodes spp.Mecklenburg County, North Carolina, USA[125]

Cynodon dactylon (star grass)Poaceae (grass family)Whole plantWeak toxic/repellentSouth America[108]

Datura stramonium L.Solanaceae (nightshade family)Seed/fruitAcaricideRwanda[151]

Delphinium brunonianum RoyleRanunculaceae (Helleboraceae) (buttercup family)LeafJuices of leaves used to destroy ticksUSA[18, 161]

Derris elliptica (Sweet) Benth.Fabaceae/Papilionaceae/Leguminosae (hardy annual, legume/pea family)Root powderAqueous solution mixed with soft soap to make an acaricideUSA[18, 150, 162164]

Digitalis purpurea L. (purple foxglove)Scrophulariaceae (Figwort family)A cardiac glycosidal (digitoxin) extractContact and dipping LC50 values were 4.08 µg cm−2 and 409.9 mg litre−1, respectively, against Hyalomma dromedarii larvaeSaudi Arabia[143]

Dioscorea polygonoides Willott (wild yam)Dioscoreaceae (yam family)Fresh leafTopical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst.Jamaica[58]

Diplophyllum africanum Turcz.Scapaniaceae (Diplophyllaceae)Whole plantAcaricideRwanda[151]

Dioscorea dumetorum (Kunth) Pax.Dioscoreaceae (yam family)RootRoots crushed in water to form a solutionTanzania[165, 166]

Dissotis throthaeMelastomataceae (melastome family)Rwanda[151]

Ervatamia divaricate L. (Burkill.) (coffee rose)ApocynaceaeFresh leafTopical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst.Jamaica[58]

Erythrina corallodendron L. (Spanish maschette)Caesalpiniaceae/Leguminosae/Papilionaceae/
Fabaceae (hardy annual, legume bean/pea family)
Fresh leafTopical application of crude ethanol extracts. Being Toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst.Jamaica[58]

Eucalyptus spp. (gum trees)Myrtaceae (myrtle family)Leaf and branchEucalyptus essential oil mixed with S. Nigra leaf extract make a repellent against Ixodes spp.USA[18, 167]

Eucalyptus spp. (gum trees)Myrtaceae (myrtle family)Leaf and branchPlant oil as an acaricideUSA[167]

Eucalyptus spp. (gum trees)Myrtaceae (myrtle family)Leaf and branchEucalyptus essential oil toxic to nymphal and larval ticks (Ixodes scapularis (Say)) at >2% concentration (wt : vol)USA[139]

Eucalyptus globulus Labill. (Tasmanian bluegum, eucalypt, and fever tree)Myrtaceae (myrtle family)Leaf and branchEucalyptus essential oil, Tick repellent against Ixodes spp.Mecklenburg County, North Carolina, USA[125]
LeafLeaf decoction is traditionally used for repelling insects and verminUSA[168]

Eupatorium odoratum Penny Clifford (Chromolaena odorata (L.) RM King and H. Robinson) (Jack in the bush)Asteraceae (daisy/aster family)Fresh leafTopical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst.Jamaica[58]

Eupatorium villosum (L.) George R. (bitter bush)Asteraceae (daisy/aster family)Fresh leafTopical application of crude ethanol extracts. Being toxic and inhabitant of embryogenesis of Boophilus microplus Canst.Jamaica[58]

Euphorbia aegyptiaca Boiss.Euphorbiaceae (spurge family)Aerial partsDiethyl ether, ethyl acetate, hexane, and ethanol extracts showed toxicity against larvae of Hyalomma dromedarii Koch, 1844Egypt[138]

Euphorbia candelabrumEuphorbiaceae (spurge family)LatexLatex as toxic/killer/acaricideKenya[140]

Euphorbia obovalifoliaEuphorbiaceae (spurge family)LatexAcaricideEthiopia[149]

Fagara microcarpa (Griseb.) Krug & Urb. (bitter bush)Rutaceae (citrus family)Fresh leafTopical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst.Jamaica[58]

Ficus brachypodaMoraceaeLatexAcaricideEthiopia[149]

Ficus cfr. burkeiMoraceaeAcaricideRwanda[151]

Foeniculum vulgare P. Mill. (Florence fennel, finocchio, anise, and sweet fennel)Umbelliferae/Apiaceae (carrot family)RootToxic to nymphal ticks (Ixodes scapularis (Say)) (LC50 = 0.744% wt : vol)USA[139]

Francoeuria crispa (Forsk.) Cass. (Francoeuria)Asteraceae (daisy/aster family)Aerial partsDiethyl ether, ethyl acetate, hexane, and ethanol extracts showed toxicity against larvae of Hyalomma dromedarii Koch, 1844Egypt[138]

Gliricidia sepium Jacq. (Aaron’s rod)Caesalpiniaceae/Leguminosae/Papilionaceae/
Fabaceae (hardy annual, legume bean/pea family)
Fresh leafTopical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst.Jamaica[58]

Gnidia kraussiana MeissnerThymelaeaceaeRootAcaricideRwanda[151]

Gynandropsis gynandra (L.) Briq. (Chisaka-Luhya, Ejobyo-Luganda, and Akeyo-Luo)CapparidaceaeAerial parts/essential oilRepellent/toxic/killerKenya[44, 104, 109, 118, 120]

Haplophyllum tuberculatum (Forsskål) A. H. L. JussieuRutaceaeAerial partsEssential oils showed toxicity effects to the larvae of Hyalomma dromedarii Koch, 1844 and Argas persicus Oken, 1818, adultsEgypt[138]

Haematoxylum campechianum L. (logwood)Caesalpiniaceae/Leguminosae/Papilionaceae/
Fabaceae (hardy annual, legume bean/pea family)
Fresh leafTopical application of crude ethanol extracts. Being toxic and inhabitant of oviposition of Boophilus microplus Canst.Jamaica[58]

Hedeoma pulegioidesL. Pers. (American Pennyroyal, mock pennyroyal, squaw mint, tickweed, stinking balm, mosquito plant)Lamiaceae previously known as Labiatae (dead-nettle or mint family)Leaf/flowerEssential oil of American pennyroyal, tick repellent against Ixodes spp.USA[125, 169, 170]

Hibiscus rosa-sinensis L. (shoe black)Malvaceae (mallow family)LeafTopical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst.Jamaica[58]

Hyacinthoides hispanica (P. Mill.) Rothm. (Endymion hispanicus (P. Mill.) Chouard) (bluebells, Spanish bluebells, Spanish squill)Liliaceae (lily family)Whole plantIt is antitick plant and confidently help heal the problems brought about by ticksUSA and South AfricaWanzala’s personal communication with Annie Berthold-Bond in USA

Hydnora johannis BeccariHydnoraceaeWhole plantAcaricideRwanda[151]

Hyparrhenia rufa (jaragua grass)Poaceae (grass family)Whole plantWeak toxic/repellentSouth America[128]

Hyptis verticillataLamiaceae previously known as Labiatae (dead-nettle or mint family)Chemosterilant that inhibits oviposition and egg hatchingCentral America[171]

Impatiens stuhlmannii Warb.Balsaminaceae (balsam, impatiens family)LeafAcaricideRwanda[151]

Iphiona rotundifoliaAsteraceae (also known as Compositae or daisy family)LeafAn acaricide infusion made from leafSomali[61]

Jatropha curcas L. (Barbados nut, purging nut, and physic nut)Euphorbiaceae (spurge family)LeafInfusion had a dipping and topical toxicity effect against Rhipicephalus appendiculatus ticks. Methanol extract repelled the ticks alsoSouth Africa[128]

Juglans nigra L.JuglandaceaeWhole plantRepellent against Ixodes spp.USA[18, 167]

Juniperus occidentalis L (Western juniper)Cupressaceae (cypress family)Heartwood and leavesToxic to nymphal and larval ticks (Ixodes scapularis (Say)) (LC50 = 0.633 and 0.073% wt : vol, resp.)USA[139]

Juniperus virginiana L (Eastern red cedar)Cupressaceae (cypress family)Heartwood and leavesToxic to nymphal and larval ticks (Ixodes scapularis (Say)) (LC50 = 0.328 and 0.001% wt : vol, resp.)USA[139]

Justicia pectoralis L. (Fresh cut)Acanthaceae (carpenter grass)Fresh leafTopical application of crude ethanol extracts. Being toxic and inhabitant of embryogenesis of Boophilus microplus Canst.Jamaica[58]

Kaliya, Pokot vernacularFruitFruit juiceKenya[153]

Lantana involucrata Roxb. (wild mint)Verbenaceae (vervain family)Fresh leafTopical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst.Jamaica[58]

Laurencia obtusa (Hudson) J. V. Lamouroux, 1813RhodomelaceaeFresh leafTopical application of crude ethanol extract affected the survival of engorged and adult female Boophilus microplus Canst. and inhibited its oviposition and embryogenesisJamaica[172]

Lavandula angustifolia (L. officinalis, L. spica, and L. vera)Lamiaceae previously known as Labiatae (dead-nettle or mint family)Leaf/flowerLavender essential oil, tick repellent against Ixodes spp.Mecklenburg County, North Carolina, USA[125]

Lepidium sativumBrassicaceae (cabbage family)SeedCrushed seeds mixed with cattle faeces and smeared on cattleEthiopia[149]

Liagora elongate
Liagora farinosa J. V. Lamouroux 1816
Liagoraceae (rhodophytes)Whole plantTopical application of crude ethanol extract affected the survival of engorged and adult female Boophilus microplus Canst. and inhibited its oviposition and embryogenesisJamaica[172]

Lippia alba L. (colic Mint)Verbenaceae (vervain family)Fresh leafTopical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst.Jamaica[58]

Lonchocarpus laxiflorusFabaceae/Papilionaceae/Leguminosae (hardy annual, legume/pea family)Floral partsRotenoids act as acaricideUSA[150]

Lupinus mutabilis Sweet (tarwi lupine/Adeans lupines/tarwi plant)Fabaceae/Papilionaceae/Leguminosae (hardy annual, legume/pea family)AcaricideEurope[91]

Majorana hortensis Mönch (sweet marjoram)Lamiaceae previously known as Labiatae (dead-nettle or mint family)LeafA blend with lemon grass and tea tree essential oils forms antitick repellent sprayNew Zealand[160]

Mammea americana L.Clusiaceae/GuttiferaeFruit and leaf/seedsToxic, sap/infusion in water/powdered seeds/decoction of seedsUSA[18, 173]

Margaritaria discoidea (Baill.) G. L. Webster (pheasant-berry, egossa red pear, or bushveld peacock-berry)Phyllanthaceae (leaf-flower family)LatexToxic/killer/acaricide. Oil hexane and water soluble extracts against the ticks Rhipicephalus appendiculatus and Amblyomma variegatumKenya[174]

Melaleuca alternifolia Cheel. (tea tree oil)Myrtaceae (myrtle family)LeafA blend with lemon grass and marjoram essential oils forms antitick repellent sprayNew Zealand[160]

Melia azedarach L. (Chinaberry, Persian lilac tree)Meliaceae (mahogany family)FruitExtracts caused mortality of Boophilus microplus larvae and inhibited partially or totally egg production and embryogenesis in engorged femalesSouth America, Brazil[175]

Melicoccus bijugatus Jacq. Guinep. Synonym: Melicocca bijuga L.SapindaceaeFresh leafTopical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst.Jamaica[58]

Melinis minutiflora Beauv. (molasses grass)Poaceae or Gramineae (the grass family)Whole plant (grass)Toxic/repellent. The plant repels ticks (Rhipicephalus appendiculatus and Boophilus microplus)South America, Caribbean, Kenya, Brazil, Mexico, Colombia, Central Africa, Southern Africa[107, 108, 119, 127, 130, 131, 134, 176], Cornell University Medicinal plants Homepage-2003

Melissa officinalis L. (lemon balm, balm, common balm, cytria, hashishat al nahil, kovanutu, ogulotu, seiyo-yama-hakka, sweet balm, toronjil, tronjan)Lamiaceae previously known as Labiatae (dead-nettle or mint family)Aerial partsEuropean pennyroyal essential oil, tick repellent against Ixodes spp.Europe and USA, Mecklenburg County, North Carolina[125]

Mesembryanthemus forsskale (Hochst)AizoaceaeAerial partsDiethyl ether, ethyl acetate, hexane, and ethanol extracts showed toxicity against larvae of Hyalomma dromedarii Koch, 1844Egypt[138]

Mentha × piperita L. (M. balsamea Willd.) (pepper mint)PiperaceaeOil repellents against Ixodes spp.USA[154]

Mentha pulegium L. (European pennyroyal, pulegium, run-by-the-ground, lurk-in-the-ditch, pudding grass, mosquito plant, fleabane, tickweed, squaw balm, squawmint tickweed)Lamiaceae previously known as Labiatae (dead-nettle or mint family)Aerial partsEuropean pennyroyal essential oil, tick repellent against Ixodes spp.Europe and USA, Mecklenburg County, North Carolina[125]

Mimosa pudica L. (shame mi lady or sensitive plant)Mimosaceae/FabaceaeFresh leafTopical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst.Jamaica[58]

Momordica charantia L. (wild cerasee)CucurbitaceaeLeafTopical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst.Jamaica[58]

Neorautanenia mitis (A. Rich) Verdc.Fabaceae/Papilionaceae/Leguminosae (hardy annual, legume/pea family)RootAcaricideRwanda[151]

Nerium oleander L. (Oleander)ApocynaceaeFresh leafTopical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst.Jamaica[58]

Nicotiana tabacum L., N. rustica, and N. glutinosaSolanaceae (nightshade family)Fresh leafLeaf extract applied as acaricide. Toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst.USA, Jamaica, and Kenya[18, 43, 58, 67, 150, 167]

Nicotiana tabacum L. (Tobacco)Solanaceae (nightshade family) Aerial partAqueous extracts had immediate effect on mortality of engorged Rhipicephalus haemaphysaloides ticks and its fecundity production of femalesIndia[177]
LeafAdd Magadi soda to the leaf to make Kupetaba, antifeedant/growth disrupting/toxic/antiovipositantKenya[43]
Whole plantA concoction mixed with sodom apple (Solanum incanum) to make an effective acaricide against brown ear tick (Rhipicephalus appendiculatus), red-legged tick (Rhipicephalus evertsii evertsi), Boophilus decoloratus, and bont tick (Amblyomma species)Kenya (Samburu pastoralists) in Baragoi[129]

Ocimum micranthum Wild. (wild parsley)Lamiaceae previously known as Labiatae (dead-nettle or mint family)LeafTopical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst.Jamaica[58]

Ocimum suave Willd.Lamiaceae previously known as Labiatae (dead-nettle or mint family)LeafOil as repellent/acaricideKenya, Tanzania[178180]

Olea europaea subsp. Cuspidata (African olive tree)Oleaceae (olive family)Whole plantA concoction mixed with Ilkerereai (Cadia purpurea) make effective acaricide against brown ear tick (Rhipicephalus appendiculatus), red-legged tick (Rhipicephalus evertsii evertsi), Boophilus decoloratus, and bont tick (Amblyomma species)Kenya (Samburu pastoralists) in Baragoi[129]

Oreopanax capitatus Jacq. (Aralia)AraliaceaeFresh leafTopical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst.Jamaica[58]

Padina vickerisiaePhaeophyceae (brown seaweeds)Whole plantTopical application of crude ethanol extract affected the survival of engorged and adult female Boophilus microplus Canst. and inhibited its oviposition and embryogenesisJamaica[172]

Peganum harmala L.ZygophyllaceaeAerial partsExtracts of petroleum ether, chloroform, ethyl acetate, and ethanol showed toxicity effects on engorged females of Boophilus annulatus Say, 1821Egypt[138]

Pelargonium graveolens L’Hérit. or P. Odoratissimum (lemon plant/rose geranium/sweet scented geranium)Geraniaceae (the stork’s bill family)Leaf/flowerRose geranium essential oil, tick repellent against Ixodes spp.Mecklenburg County, North Carolina, USA[125]

Pennisetum clandestinum (Kikuyu grass)Gramineae/Poaceae (grass family)Whole plantWeak toxic/repellentSouth America[108]

Pennisetum typhoidesGramineae/Poaceae (grass family)Corn and stemPowder/dustSouthern Africa and Niger[127, 181]

Petiveria alliacea L. (Guinea hen)PhytolaccaceaeLeaf, rootTopical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. Crude ethanol extracts exhibit some repellent activity against B. Microplus Canst. Dibenzyltrisulfide, a compound in the roots of P. alliacea, is acaricidalJamaica; Central and South America, Caribbean and Africa[58, 182] Cornell University Medicinal plants Homepage-2003

Peucedanum angolense (Welw.)Apiaceae (carrot family)LeafAcaricideRwanda[151]

Physostigma mesoponticum Taub.Fabaceae/Papilionaceae/Leguminosae (hardy annual, legume/pea family)Tuber, leaf, bark, rootAn infusionMalawi[96]

Phytolacca dodecandra L’Herit.PhytolaccaceaeLeafJuice; acaricideRwanda, Ethiopia[149, 151]

Pimenta dioica L. (pimento)MyrtaceaeFresh leafTopical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst.Jamaica[58]

Pimenta racemosa (West Indian bay tree, bay rum tree, wild cinnamon, and bayberry)MyrtaceaeLeafBay essential oil, repellent against ticks (Ixodes spp.)Mecklenburg County, North Carolina, USA[125]

Piper amalago L. (black jointer)PiperaceaeFresh leafTopical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst.Jamaica[58]

Piper auritum H. B. & K.PiperaceaeWhole plant partsJuiceUSA[18]

Piper auritum H. B. & K.PiperaceaeWhole plantJuiceCentral America[183]

Piper capense L. f.PiperaceaeLeafAcaricideRwanda[151]

Piqueria trinervia Cav.CompositaeLeaf/flower/rootPiquerols A and B as acaricide against Boophilus microplus Canst.South America[184]

Pongamia pinnata Vent. (Indian beech, Pongam oil tree)Fabaceae/Papilionaceae/Leguminosae (hardy annual, legume/pea family)SeedPongamia essential oil is used as acaricide against Boophilus microplus Canst.India[145]

Pseudotsuga menziesii (Mirbel) Franco var. menziesii (formerly P. taxifolia) (Douglas-fir, Douglasfir)Pinaceae (pine family)Wood pitchToxic to nymphal and larval ticks (Ixodes scapularis (Say)) at >2% concentration (wt : vol)USA[139]

Psiadia punctulata (DC) VatkeAsteraceae/Compositae (daisy family)Whole plantA concoction mixed with aloe (Aloe secundiflora) effective acaricide against brown ear tick (Rhipicephalus appendiculatus), red-legged tick (Rhipicephalus evertsii evertsi), Boophilus decoloratus, and bont tick (Amblyomma species)Kenya (Samburu pastoralists) in Baragoi[129]

Ptaeroxylon obliquum RadlkPtaeroxylaceaeAn infusion of the powder as a washSouthern Africa[18, 127]

Ranunculus multifidus Forsk.Ranunculaceae (buttercup family)FruitAcaricideRwanda[151]

Reaumuria hirtella (Jaub. & Spach)TamaricaceaeAerial partsDiethyl ether, ethyl acetate, hexane, and ethanol extracts showed toxicity against larvae of Hyalomma dromedarii Koch, 1844Egypt[138]

Rhoicissus tridentataVitaceaePlant partsAcaricideRwanda[151]

Ricinus communis L. (castor oil plant)Euphorbiaceae (spurge family) LeafTopical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst.Jamaica[58]
SeedCustard seed oil as an acaricideIndia[144]
LeafDichloromethane extracts were repellent to Rhipicephalus appendiculatusSouth Africa[128]

Rosmarinus officinalis L. (rosemary)Lamiaceae previously known as Labiatae (dead-nettle or mint family)LeafRosemary essential oil, repellent against ticks (Ixodes spp.)Mecklenburg County, North Carolina, USA[125]

Stylosanthes scabra cv. Fitzroy or SecaFabaceae (hardy annual, legume/pea family)Whole plant (grass)Toxic to Boophilus microplus Canst.South America[110]

Salvia serotina L./Wild. (little woman/chicken weed)Lamiaceae previously known as Labiatae (dead-nettle or mint family)Fresh leafTopical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst.Jamaica[58]

Sambucus nigra spp. Canadensis (S. canadensis) L. (American Elder or elderberry/European elder)Adoxaceae/Caprifoliaceae (honeysuckle family)LeafExtracts as acaricidesUSA[167]

Sambucus nigra spp. Canadensis (S. canadensis) L. (American Elder or elderberry/European elder)Adoxaceae/Caprifoliaceae (honeysuckle family)LeafLeaf extract mixed with tobacco dust and Eucalyptus oilUSA[18, 167]

Sclerocarya caffra Sond.AnacardiaceaeFruitAcaricideSouth Africa/East Africa/Madagascar[18, 127]

Securidaca longipedunculata Fres.PolygalaceaePlantAcaricideRwanda[151]

Sequoia sempervirens L. (redwood, coast redwood, and California redwood)Taxodiaceae (bald cypress family)/Cupressaceae (cypress family)Heartwood and leavesToxic to nymphal and larval ticks (Ixodes scapularis (Say)) (LC50 = 0.1.673 and 0.079% wt : vol, resp.)USA[139]

Sequoiadendron giganteum (Lindl.) J. Buchholz (giant sequoia, big tree, giant redwood)TaxodiaceaeHeartwood and leavesToxic to nymphal and larval ticks (Ixodes scapularis (Say)) at >2% concentration (wt : vol)USA[139]

Senna italica subsp. arachoides (Mill.) Goora wall. (Italian senna)Fabaceae (hardy annual, legume/pea family)RootThe acaricidal activity of the ethyl acetate root extract increased significantly with concentration when tested against Hyalomma marginatum rufipesSouth Africa[185]

Sida acuta Burm. (broom weed)MalvaceaeFresh leafTopical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst.Jamaica[58]

Silybum marianum (L.) Gaertn. (Milk thistle)AsteraceaeAerial partsExtracts of petroleum ether, chloroform, ethyl acetate, and ethanol showed toxicity effects on engorged females of Boophilus annulatus Say, 1821Egypt[138]

Simarouba glauca DC. (Bitter wood)Simaroubaceae (quassia family)Fresh leafTopical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst.Jamaica[58]

Simmondsia chinensis (Link) C. K. Schneid. (jojoba, goat nut, deer nut, pignut, wild hazel, quinine nut, coffeeberry, or gray box bush)SimmondsiaceaeAerial partsExtracts caused motalities and affected reproductive physiology of the adult female tick, Boophilus annulatusEgypt[186]

Solanum dasyphyllum Schum. et Thonn.Solanaceae (nightshade family)Fruit, leaf, stemAcaricideRwanda[151]

Solanum incanum (sodom apple) Solanaceae (nightshade family)FruitJuiceEthiopia[149]
Whole plantA concoction mixed with tobacco (Nicotiana tabacum) to make an effective acaricide against brown ear tick (Rhipicephalus appendiculatus), red-legged tick (Rhipicephalus evertsii evertsi), Boophilus decoloratus, and bont tick (Amblyomma species)Kenya (Samburu pastoralists) in Baragoi[129]

Sorghum bicolor (L.) Moench (sorghum)Poaceae (grass family)Whole plantExtracts caused motalities and affected reproductive physiology of the adult female tick, Boophilus annulatusEgypt[186]
Aerial partAffects livestock ticksKenya[47]

Spigelia anthelmia L. (worm grass)Loganiaceae (Logania family)Fresh leafTopical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst.Jamaica[58]

Stachytarpheta jamaicensis Wild. (vervine)Verbenaceae (verbena/vervain family)Fresh leafTopical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst.Jamaica[58]

Stemona collinsae Craib.Stemonaceae (Stemona family)Whole plant50% concentration of extract caused 100 and 93.33% mortalities of engorged nymphs and adults of Boophilus microplus Canst., respectivelyThailand[187]

Stemona tuberosa Lour.Stemonaceae (Stemona family)Whole plant5% of chlorhydric acid extracts killed larvae of Rhipicephalus sanguineus, Boophilus microplus and Haemaphysalis intermedia ixodid ticksVietnam[188]

Strychnos madagascariensis Poir. (black monkeys)LoganiaceaeLeafInfusion had a strong dipping and topical toxicity effect against Rhipicephalus appendiculatus ticks. The extract showed repellence activity against R. appendiculatusSouth Africa[128]

Stylosanthes hamata cv. Verano.Fabaceae (pea family)Whole plant (grass)Toxic/repellent against Boophilus microplus Canst.South America,[189192]
Australia[110, 111]

Stylosanthes humilis H. B. K.Fabaceae (pea family)Whole plant (grass)Toxic/repellent against Boophilus microplus Canst.South America[189192]

Stylosanthes scabra Vogel. (shrubby stylo)Fabaceae (pea family)Whole plantExtracts caused a high larval mortality of Rhipicephalus sanguineus, Boophilus microplus, and Haemaphysalis intermedia ixodid ticksIndia[193]

Stypopodium lobalum (C. Agardh) Kützing.Dictyotaceae (thalloid brown alga)Whole plantTopical application of crude ethanol extract affected the survival of engorged and adult female Boophilus microplus Canst. and inhibited its oviposition and embryogenesisJamaica[172]

Symphytum officinale L. (Comfrey)Boraginaceae (borage family)Fresh leafTopical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst.Jamaica, USA[58]

Tabernaemontana johnstoniiApocynaceaeAcaricideRwanda[151]

Tagetes minuta L. (marigold)Asteraceae (daisy family). Aerial partsExtracted essential oil had significant repellent effect against Rhipicephalus appendiculatus adult ticksKenya[47, 194]
Extracted essential oil had significant repellent effect against Hyalomma rufipes adult ticksSouth Africa[195]

Tagetes patula French (marigold, dwarf marigold, or dwarf French marigold)Asteraceae (daisy family)Rwanda[151]

Tamarindus indicus L. (tamarind)Caesalpiniacae (gulmohar family)Mature fruitWater and 10% ethanol crude extracts caused mortality of engorged female, Boophilus microplus Canst.
Organic acids in tamarind fruits (oxalic, malic, succinic, citric and tartaric acids) also caused mortality of B. microplus Canst.
Thailand[196]

Tanacetum vulgareAsteraceae ([also known as Compositae] daisy family)Whole plantEssential oils are acaricidalEurope, Eastern North Americahttp://www.florahealth.com/home_int.cfm

Taxodium distichum (L.) L. C. Rich. (bald cypress and swamp Cypress)Taxodiaceae (bald cypress family)Heartwood and leavesToxic to nymphal and larval ticks (Ixodes scapularis (Say)) at >2% concentration (wt : vol)USA[139]

Tephrosia leiocarpa A. GrayFabaceae/Papilionaceae/Leguminosae (hardy annual, legume/pea family)RootAcaricideNorth America[197]

Tephrosia vogelii Hook F.Fabaceae/Papilionaceae/Leguminosae (hardy annual, legume/pea family)Leaf, root, pod, seed, bark, whole plantRotenoids present in an infusion acts like modern dips. Toxic to 1-, 2-, and 3-host ticksCameroon, USA, Malawi, Tanzania[18, 150, 198202]

Thuja plicata Donn ex D. Don in Lambert 1824 (Western/giant red cedar, giant arborvitae, shinglewood, canoe cedar)Cupressaceae (cypress family)Heartwood and leavesToxic to nymphal and larval ticks (Ixodes scapularis (Say)) (LC50 = 0.821 and 0.022% wt : vol, resp.)USA[139]

Thylachium africanum Lour.CapparidaceaeAerial parts/oilRepellency of their essential oilKenya[104]

Turnera ulmifolia L. (ramgoat dashalong)TurneraceaeFresh leafTopical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst.Jamaica[58]

Turpentine, name applied to numerous semifluid, yellow or brownish oleoresins obtained from various coniferous trees in Asia, Europe, and America Turpentine, Syncarpia glomuliferaMyrtaceaeAcaricideUSA[150]

Urena lobata L. (bur mallow)MalvaceaeFresh leafTopical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst.Jamaica[58]

Vernonia amygdalina L. (bitter-leaf tree)Asteraceae (also known as Compositae or daisy family)LeafJuiceEthiopia[149]

Vitex agnus-castus L. (chaste tree, chasteberry, Abraham’s balm, or monk’s pepper)LamiaceaeAerial partsEthanol, propylene carbonate, Vitex agnus-castus concentrate, topical application, repelling horseflies, flies and mosquitoesSwitzerland[203]

Wedelia trilobata L. (yellow marigold)Asteraceae (also known as Compositae or daisy family)Fresh leafTopical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst.Jamaica[58]

Zingiber officinale Wild. (Ginger)ZingiberaceaeFresh leafTopical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst.Jamaica[58]