Evaluation of Analgesic Activity of Papaver libanoticum Extract in Mice: Involvement of Opioids Receptors

Table 3

Comparison of AUC of different doses of PLE and morphine.

Treatment	Tail flick method			Hot plate method
	AUC	Response peak (sec)	Time (hrs)	AUC	Response peak (sec)	Time (hrs)
Morphine (5 mg/kg)	16.85	8.5	0.5	52.83	14.33	0.5
PLE 75 mg/kg	18.04	3.57	3	53.93	9.44	3
PLE 100 mg/kg	23.38	4.59	3	54.26	10.38	3
PLE 150 mg/kg	29.66	5.6	3	67.73	12.47	3
PLE 200 mg/kg	33.58	7.18	3	72.96	14.12	3