Number Trial number status Conditions and dosage Objectives Interventions Outcomes Number of subjects (age/ Recruiting study locations (1) ChiCTR-IOR-15007587 (pending)Obesity To evaluate the effectiveness and safety of the empirical formula—Xiere Huazhuo Formula of Chinese Medicine Professor—Ding Xueping in obesity treatment I: Xiere Huazhuo granule; C: orlistat 1: weight, body fat distribution, blood lipid, insulin resistance HOMA-2, adipokines 48 (18–65/F-M) December 14, 2015 China (2) NCT00383058 (completed)Obesity To examine whether extract of the green tea is effective on obese women I: the extract of green tea; C: placebo Body mass index, body weight, glucose, cholesterol, LDL, HDL, triglyceride 100 (16–60/F) September 29, 2009 China (3) NCT02605655 (completed)Metabolic syndrome X (1 g/day for 3 months) To determine whether the Chinese formula AMP-1915 has effect on metabolic syndrome (MS) in MS patients I: AMP-1915 (Astragalus, Radix Puerariae, Cortex Mori); C: placebo FBG, plasma lipid levels, plasma insulin concentration, body weight, HbA1c 60 (40–65/F-M) April 1, 2015 China (4) NCT01142076 (completed)Overweight (170 mL/day, 24 weeks) To examine the treatment of adiposity (stagnation of QI causing phlegm retention) I: Xinju Xiaogao Prescription; C: placebo Waistline, BMI 140 (16–80/F-M) March 1, 2011 China (5) NCT02651454 (recruiting)Obesity (6 g, three times a day, 12 weeks) To investigate the efficacy and safety of Daesiho-tang and Taeeumjowi-tang on Korean obese women with metabolic syndrome risk factors I: Daesiho-tang: Jowiseungcheung-tang; C: placebo Body weight, body fat percentage, fat mass, waist circumference, body mass index, lipid profile 120 (18–65/F) January 5, 2016 Korea (6) NCT02337933 (completed)Metabolic syndrome X (150 mg, once a day, 12 weeks) To evaluate the effect of ursolic acid on the insulin sensitivity and metabolic syndrome I: ursolic acid; C: placebo Total insulin sensitivity, waist circumference, fasting glucose levels, body weight, BMI 24 (30–60/F-M) September 1, 2015 Mexico (7) NCT01724099 (recruiting)Obesity (3 times per day, 12 weeks) To evaluate the effect of Euiiyin-tang on obese patients I: Euiiyin-tang; C: placebo Weight, C-reactive protein, blood pressure, blood glucose, waist/hip ratio 160 (18–65/F) November 2, 2012 Korea (8) NCT02929849 (ongoing)Obesity (300 mg, 500 mg/day) To determine whether an herb with known alpha-glucosidase inhibitor properties (Salacia chinensis , SC), affecting postprandial appetite ratings and glucose indices in overweight/obese individuals I: Salacia chinensis ; C: placebo Appetite ratings, glucose indices, gut hormones 59 (20–59/F-M) August 16, 2016 United States (9) NCT01778257 (completed)Obesity (mate extract (3150 mg/day), 12 weeks) To evaluate efficacy and safety of mate extracts on decrement of body and abdominal fat in obese subjects I: mate extract; C: placebo Body and abdominal fat, weight, BMI, waist and hip circumference 30 (19–65/F-M) March 1, 2012 Korea (10) NCT01709955 (completed)Obesity (750 mg of Glucomannan in capsule form) To determine if the herb, Glucomannan, is an effective nonpharmacological appetite suppressant for overweight or class I obese patients I: Glucomannan, C: placebo Weight 43 (21–60/F-M) July 1, 2011 United States (11) NCT00502658 (completed)Overweight, obesity (dose is unknown, 12 weeks) To evaluate the effect of dietary supplements (shakes and supplements) and personal energy tracking device to promote and maintain healthy weight I: dietary supplement containing vitamins, minerals, and herbs; C: dietary supplement Body weight, biophotonic scanner 120 (18–65/F-M) December 1, 2007 United States (12) NCT00823381 (completed)Obesity, metabolic syndrome (75 mg once a day) To evaluate the effects of the antioxidant “resveratrol” to a diet intervention (calorie restriction) I: resveratrol, C: placebo Insulin sensitivity, body composition, blood lipid levels 58 (35–70/F) December 1, 2013 United States (13) NCT02613715 (completed)Overweight and obesity (250 mL of blackberry juice) To evaluate the bioavailability of blackberry juice anthocyanins in normal weight and overweight/obese adults I: blackberry juice Plasma concentrations of anthocyanins and anthocyanin metabolites 18 (18–40/M-F) June 2015 Portugal (14) NCT01705093 (unknown)Childhood obesity; cardiovascular disease (50 g of flavonoid-rich freeze-dried strawberry powder) To verify if strawberry intake can lead to improvements in select measures of cardiovascular function in overweight and obese adolescent males I: flavonoid-rich freeze-dried strawberry powder Vascular functionmeasured by peripheralarterial tonometry 25 (14–18/M) August 2012 United States (15) NCT01138930 (unknown)Polycystic ovary syndrome; obesity (1.5 g daily for 3 months) To examine the effect of berberine metabolic and hormonal parameters and insulin resistance in obese patients with polycystic ovary syndrome I: berberine; C: placebo Body insulin action, Weight, waist/hip circumference, OGTT 120 (18–35/F) June 7, 2010 China (16) NCT01471275 (unknown)Type 2 diabetes mellitus; obesity; high triglycerides (15 g each time, twice a day, with boiled water) Evaluate the safety and efficacy of Jiang Tang Tiao Zhi decoction in treatment of obesity with type 2 diabetes, dyslipidemia I: Jiang Tang Tiao Zhi decoction; C: metformin Glycosylated hemoglobin, waistline, triglycerides, liver function 450 (30–65/F-M) November 14, 2011 China
