Research Article

Activation of AMPK by Buddleja officinalis Maxim. Flower Extract Contributes to Protecting Hepatocytes from Oxidative Stress

Table 2

General histomorphometrical analysis of acute CCl4-treated mouse hepatic tissues.

GroupsPercentages of degenerative regions (%/mm2 of hepatic parenchyma)Numbers of inflammatory cells infiltrated (cells/mm2 of hepatic parenchyma)Numbers of degenerative hepatocytes (cells/1000 hepatocytes)

Controls
 Intact
 BFE (100 mg/kg)
 CCl4
CCl4 + BFE-treated mice
 30 mg/kg
 100 mg/kg

Values are expressed as means ± SD of 10 histological fields. CCl4: carbon tetrachloride; BFE: Buddleja officinalis Maxim. flower extract.
as compared with intact control by MW test; as compared with CCl4 control by MW test.