Hepatotoxicity in Rats Induced by Aqueous Extract of Polygoni Multiflori Radix, Root of Polygonum multiflorum Related to the Activity Inhibition of CYP1A2 or CYP2E1

Figure 3

The rat serum transaminases levels assayed at 2 h, 4 h, 24 h, 48 h, and 72 h after oral administration of PMR . (a) and (b) for ALT level; (c) and (d) for AST level; (a) and (c) for CYP1A2 inhibited group; (b) and (d) for CYP2E1 inhibited group. difference compared with other groups, . significant difference compared with other groups, .

(a)

(b)

(c)

(d)