Long-Term Intake of Uncaria rhynchophylla Reduces S100B and RAGE Protein Levels in Kainic Acid-Induced Epileptic Seizures Rats

Figure 2

Alteration of electroencephalographic (EEG) signals in KA-injected rats. Baseline EEG activity in the sensorimotor cortex was characterized by 6–8 Hz activity in rats when awake (a). KA-induced temporal lobe seizures, including wet-dog shakes (WDS) with intermittent polyspike-like activity (b), facial myoclonia with continuous sharp waves (c), and paw tremor (PT) with continuous-spike activity (d). Each type of seizures had its own characteristic EEG activity. Lt Cx: EEG recording of the left sensorimotor cortex; Rt Cx: EEG recording of the right sensorimotor cortex; EMG: EMG recording of the neck muscles.

(a)

(b)

(c)

(d)