Synergistic Uric Acid-Lowering Effects of the Combination of Chrysanthemum indicum Linne Flower and Cinnamomum cassia (L.) J. Persl Bark Extracts
Table 2
XOD activity of CF, CB, and CC12 mixture and their marker compounds.
Sample treatment
Concentration (μg/ml)
% inhibition
IC50 (μg/ml)
CF
100
5.3 ± 2.8
>500
250
8.9 ± 4.1
500
39.2 ± 6.9
CB
100
31.2 ± 2.6
143
250
100.3 ± 3.1
500
98.4 ± 0.1
CC12 mixture
100
23.2 ± 0.4
153.8
250
94.3 ± 3.2
500
101.0 ± 0.2
Chlorogenic acid
62.5
24.0 ± 1.7
103.8
125
63.6 ± 1.5
250
107.3 ± 0.6
3,4-Dicaffeoylquinic acid
62.5
21.0 ± 1.5
79.7
125
104.6 ± 2.6
250
85.0 ± 1.2
Coumarin
62.5
22.8 ± 0.1
95.2
125
75.1 ± 1.0
250
103.9 ± 0.7
Cinnamaldehyde
62.5
101.2 ± 3.2
43.7
125
126.3 ± 5.6
250
118.8 ± 35.1
trans-Cinnamic acid
62.5
54.3 ± 0.7
58.8
125
96.7 ± 1.9
250
114.9 ± 0.4
o-Methoxycinnamaldehyde
62.5
104.7 ± 0.2
25.7
125
101.2 ± 0.2
250
100.0 ± 0.4
Allopurinol
6.25
51.7 ± 0.7
12.5
71.7 ± 0.1
25
80.3 ± 0.3
Chrysanthemum indicum Linne flower ethanol extract; CB, Cinnamomum cassia (L.) J. Persl bark ethanol extract; CC, mixture of CF and CB. Data are expressed as the .
