Potent Phosphodiesterase Inhibition and Nitric Oxide Release Stimulation of Anti-Impotence Thai Medicinal Plants from “MANOSROI III” Database

Table 6

Sexual behavior stimulatory effect on intromission frequency and ejaculatory frequency in paroxetine-induced sexual dysfunction male mice () after daily oral administration of the EDP1-001(1) extract for 1, 7, and 14 days.

Day	Intromission frequency					Ejaculatory frequency
	Distilled water	Sildenafil	EDP1-001(1) extract			Distilled water	Sildenafil	EDP1-001(1) extract
			Frequency	Fold1	Fold2			Frequency	Fold1	Fold2
1				0.26	0.07				0	0
7				—	0.02				—	0
14				109.09	0.53				—	0.62

Fold₁ was calculated by comparing with the control group (orally administered with distilled water); Fold₂ was calculated by comparing with the positive control group (orally administered with sildenafil).